Labference: Benchmarking the Reasoning-Action Connection in Robotic Laboratories

Realizing Embodied AI for Science requires robots to translate experimental goals into reliable physical procedures, reducing hazardous and repetitive human work while generating evidence for scientific discovery. Although language-based planning and learned manipulation provide complementary capabilities, their integration requires robots to adapt subsequent operations to actual execution outcomes. For example, an unsuccessful placement changes what must be done next, even when the experimental goal remains unchanged. Existing benchmarks assess planning, manipulation, and laboratory workflows through task completion and reasoning or execution metrics; however, aggregate performance leaves the connection between outcome-dependent choices and physical execution unresolved. To address this evaluation gap, we introduce Labference, a benchmark for evaluating how observed physical outcomes guide subsequent choices and how those choices translate into robotic laboratory actions. Its evaluation protocol is designed to test outcome-dependent behavioral adaptation through controlled evidence variations, while independently measuring operation selection, physical execution, and task completion. Matched Oracle-assisted continuations from shared checkpoints then assess which forms of support improve subsequent choices and task completion. Initial weighing evaluations reveal target-selection errors in the tested VLA policies despite successful object transfers, whereas GPT-driven control achieves correct selection but encounters execution failures and substantial computation costs. Together, these findings highlight the need to connect task-appropriate reasoning with reliable, timely action. By making this connection measurable and diagnosable, Labference supports targeted improvements toward autonomous experimentation for Embodied AI for Science.