Cost Reductions with Oral Step-Down Antibiotic Treatment by Causative Microorganism in Infective Endocarditis: A POET Trial Analysis

Iversen K et al. Partial oral versus intravenous antibiotic treatment of endocarditis. N Engl J Med. 2019;380(5):415-24. Delgado V et al.; ESC Scientific Document Group. 2023 ESC Guidelines for the management of endocarditis. Eur Heart J. 2023;44(39):3948-4042. Erratum in: Eur Heart J. 2023;44(45):4780. Erratum in: Eur Heart J. 2024;45(1):56. Pries-Heje MM et al. Five-year outcomes of the Partial Oral Treatment of Endocarditis (POET) trial. N Engl J Med. 2022;386(6):601-2. Pries-Heje MM et al. Clinical implementation of partial oral treatment in infective endocarditis: the Danish POETry study. Eur Heart J. 2023;44(48):5095-106. Kader N et al. Costs of oral step-down antibiotic treatment versus intravenous hospital antibiotic treatment in patients with endocarditis: cost analysis from the POET randomized trial. Circ Popul Health Outcomes. 2026;DOI:10.1161/CIRCOUTCOMES.126.014059. Tzoumas A et al. Epidemiological profile and mortality of infective endocarditis over the past decade: a systematic review and meta-analysis of 133 studies. Am J Cardiol. 2025;244:67-88. Strange JE et al. Patient characteristics, microbiology, and mortality of infective endocarditis after transcatheter aortic valve implantation. Clin Infect Dis. 2023;77(12):1617-25. Philip M et al.; EURO-ENDO Investigators. Clinical characteristics, management and outcomes of enterococcal infective endocarditis: an ancillary study from the ESC-EORP EURO-ENDO registry. Eur Heart J Qual Care Clin Outcomes. 2026;12(3):308-21. Fowler Jr VG et al.; ICE Investigators. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA. 2005;293(24):3012-21.

Authors

Publication Details

Journal
EMJ Cardiology
Published
2026-10-27
DOI
https://doi.org/10.33590/emj/d6416ub6
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Cost Reductions with Oral Step-Down Antibiotic Treatment by Causative Microorganism in Infective Endocarditis: A POET Trial Analysis

Kader
2 links
EMJ Cardiology
Infective Endocarditis Diagnosis and Management
article

Cost Reductions with Oral Step-Down Antibiotic Treatment by Causative Microorganism in Infective Endocarditis: A POET Trial Analysis

Kader
article en

Abstract

Iversen K et al. Partial oral versus intravenous antibiotic treatment of endocarditis. N Engl J Med. 2019;380(5):415-24. Delgado V et al.; ESC Scientific Document Group. 2023 ESC Guidelines for the management of endocarditis. Eur Heart J. 2023;44(39):3948-4042. Erratum in: Eur Heart J. 2023;44(45):4780. Erratum in: Eur Heart J. 2024;45(1):56. Pries-Heje MM et al. Five-year outcomes of the Partial Oral Treatment of Endocarditis (POET) trial. N Engl J Med. 2022;386(6):601-2. Pries-Heje MM et al. Clinical implementation of partial oral treatment in infective endocarditis: the Danish POETry study. Eur Heart J. 2023;44(48):5095-106. Kader N et al. Costs of oral step-down antibiotic treatment versus intravenous hospital antibiotic treatment in patients with endocarditis: cost analysis from the POET randomized trial. Circ Popul Health Outcomes. 2026;DOI:10.1161/CIRCOUTCOMES.126.014059. Tzoumas A et al. Epidemiological profile and mortality of infective endocarditis over the past decade: a systematic review and meta-analysis of 133 studies. Am J Cardiol. 2025;244:67-88. Strange JE et al. Patient characteristics, microbiology, and mortality of infective endocarditis after transcatheter aortic valve implantation. Clin Infect Dis. 2023;77(12):1617-25. Philip M et al.; EURO-ENDO Investigators. Clinical characteristics, management and outcomes of enterococcal infective endocarditis: an ancillary study from the ESC-EORP EURO-ENDO registry. Eur Heart J Qual Care Clin Outcomes. 2026;12(3):308-21. Fowler Jr VG et al.; ICE Investigators. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA. 2005;293(24):3012-21.

EMJ Cardiology
Good health and well-being
Openalex Percentile: Top 12%
Infective Endocarditis Diagnosis and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon