What are the recommended prophylactic treatments for adults with chronic migraine?

High-confidence evidence supports fremanezumab, galcanezumab, and onabotulinumtoxinA as effective prophylactic treatments for chronic migraine in adults, with moderate evidence for agents like topiramate and erenumab. Treatment choice should consider patient-specific factors, including response variability and side effect profiles.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-27
DOI
https://doi.org/10.5281/zenodo.23681685
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

What are the recommended prophylactic treatments for adults with chronic migraine?

Tripdatabase
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Zenodo (CERN European Organization for Nuclear Research)
Migraine and Headache Studies
article

What are the recommended prophylactic treatments for adults with chronic migraine?

Tripdatabase
article en

Abstract

High-confidence evidence supports fremanezumab, galcanezumab, and onabotulinumtoxinA as effective prophylactic treatments for chronic migraine in adults, with moderate evidence for agents like topiramate and erenumab. Treatment choice should consider patient-specific factors, including response variability and side effect profiles.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 12%
Migraine and Headache Studies
DOIOpen Access PDFOpenAlex
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What are the recommended prophylactic treatments for adults with chronic migraine? — Tripdatabase · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS