Thermomechanical Noise Dilution by Low‐Q Cavity for Nanoparticles Detection

ABSTRACT Phonon laser sensors offer powerful label‐free detection, yet their sensitivity remains bounded by noise for which robust suppression strategies are still lacking. Here we introduce a technique for diluting thermomechanical noise that counter‐intuitively selects lower‐Q optical modes to suppress thermal fluctuations of phonon‐laser frequency, followed by active feedback locking for frequency stabilization. The combined approach enables real‐time detection of single 10 nm‐radius polystyrene particles based on a microbubble cavity with a 38 MHz phonon mode, estimating a mass limit of . We further apply the platform to study iron–oxide uptake and reaction dynamics in cells.

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Publication Details

Journal
Laser & Photonics Review
Published
2026-10-27
DOI
https://doi.org/10.1002/lpor.72116
Primary Topic
Mechanical and Optical Resonators
Type
article
Field-Weighted Citation Impact
0.00

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Thermomechanical Noise Dilution by Low‐Q Cavity for Nanoparticles Detection

Hao Tian, Fang‐Wen Sun, Chun‐Hua Dong, Xi‐Feng Ren et al.
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Laser & Photonics Review
Mechanical and Optical Resonators
article

Thermomechanical Noise Dilution by Low‐Q Cavity for Nanoparticles Detection

Hao Tian, Fang‐Wen Sun, Chun‐Hua Dong, Xi‐Feng Ren, Zhen Shen, Yu Wang, Guo G, Rui Niu, Yu‐Xuan Chen, Yi‐Wen Huang, Gui‐Wen Zheng, Tian Tian
article en

Abstract

ABSTRACT Phonon laser sensors offer powerful label‐free detection, yet their sensitivity remains bounded by noise for which robust suppression strategies are still lacking. Here we introduce a technique for diluting thermomechanical noise that counter‐intuitively selects lower‐Q optical modes to suppress thermal fluctuations of phonon‐laser frequency, followed by active feedback locking for frequency stabilization. The combined approach enables real‐time detection of single 10 nm‐radius polystyrene particles based on a microbubble cavity with a 38 MHz phonon mode, estimating a mass limit of . We further apply the platform to study iron–oxide uptake and reaction dynamics in cells.

Laser & Photonics Review
University of Science and Technology of China (CN), Harbin Institute of Technology (CN), Quantum Design (Germany) (DE), QuantumCTek (China) (CN), Nanjing Medical University (CN)
National Natural Science Foundation of China, University of Science and Technology of China, National Science and Technology Major Project, Natural Science Foundation of Anhui Province, Fundamental Research Funds for the Central Universities
Openalex Percentile: Top 20%
Mechanical and Optical Resonators
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Thermomechanical Noise Dilution by Low‐Q Cavity for Nanoparticles Detection — Hao Tian, Fang‐Wen Sun, et al. · Laser & Photonics Review (2026) | TGRS Research Map | TGRS