Anodal tDCS alters perceived visual contrast in humans

Cortical gain modulation is thought to alter perceptual experience, most prominently demonstrated by the effects of spatial attention on contrast appearance. Whether externally induced changes in cortical excitability produce comparable perceptual consequences remains unclear. Here, we tested whether anodal transcranial direct current stimulation (tDCS) over occipital cortex alters perceived contrast. Using a contrast-appearance paradigm, participants judged which of two gratings appeared higher in contrast. Anodal stimulation produced systematic shifts in the point of subjective equality (PSE), such that stimuli presented in the contralateral visual field were perceived as higher in contrast. This effect reversed across stimulus configurations and was absent under sham stimulation, ruling out response bias. Psychometric slopes did not change significantly, consistent with stable discrimination precision around the PSE. These findings demonstrate that tDCS alters contrast appearance, suggesting that changes in cortical excitability can directly influence perceptual experience through gain-like modulation of sensory responses.

Authors

Institutions

Publication Details

Journal
iScience
Published
2026-10-27
DOI
https://doi.org/10.1016/j.isci.2026.118005
Primary Topic
Transcranial Magnetic Stimulation Studies
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Anodal tDCS alters perceived visual contrast in humans

Yosun Yoon, Sang Wook Hong
iScience
Transcranial Magnetic Stimulation Studies
article

Anodal tDCS alters perceived visual contrast in humans

Yosun Yoon, Sang Wook Hong
article en

Abstract

Cortical gain modulation is thought to alter perceptual experience, most prominently demonstrated by the effects of spatial attention on contrast appearance. Whether externally induced changes in cortical excitability produce comparable perceptual consequences remains unclear. Here, we tested whether anodal transcranial direct current stimulation (tDCS) over occipital cortex alters perceived contrast. Using a contrast-appearance paradigm, participants judged which of two gratings appeared higher in contrast. Anodal stimulation produced systematic shifts in the point of subjective equality (PSE), such that stimuli presented in the contralateral visual field were perceived as higher in contrast. This effect reversed across stimulus configurations and was absent under sham stimulation, ruling out response bias. Psychometric slopes did not change significantly, consistent with stable discrimination precision around the PSE. These findings demonstrate that tDCS alters contrast appearance, suggesting that changes in cortical excitability can directly influence perceptual experience through gain-like modulation of sensory responses.

iScienceVol. 29(11)
Florida Atlantic University (US)
Florida Atlantic University
Good health and well-being
Openalex Percentile: Top 18%
Transcranial Magnetic Stimulation Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon