Protocol for dynamic eye-brain imaging by integrating an eye-tracking system with magnetic resonance imaging
Magnetic resonance imaging (MRI) is essential for examining ocular pathologies, but conventional protocols are prone to motion artifacts caused by eye movements. Here, we present a protocol for integrating eye tracking (ET) with MRI to achieve high-resolution, motion-robust imaging of the eye. We describe acquisition, reconstruction, and post-processing steps combining ET and MRI data. This approach improves structural detail, enhances image quality, and strengthens MRI’s diagnostic value in ophthalmology while paving the way for replacing hardware-based ET with machine learning solutions. For complete details on the use and execution of this protocol, please refer to Franceschiello et al. 1 1. Franceschiello, B. ∙ Di Sopra, L. ∙ Minier, A. ... 3-Dimensional magnetic resonance imaging of the freely moving human eye Prog. Neurobiol. 2020; 194 , 101885 Crossref Scopus (15) PubMed Google Scholar
Authors
- Eleonora Fornari (ORCID: https://orcid.org/0000-0002-4398-8640)
- Elena Najdenovska (ORCID: https://orcid.org/0000-0002-5799-9316)
- Benedetta Franceschiello (ORCID: https://orcid.org/0000-0003-0754-5081)
- Oscar Estéban (ORCID: https://orcid.org/0000-0001-8435-6191)
- Laura Elena Raileanu (ORCID: https://orcid.org/0000-0001-9045-5620)
- Célio Carvalho (ORCID: https://orcid.org/0009-0002-9719-2477)
- Micah M. Murray (ORCID: https://orcid.org/0000-0002-7821-117X)
- Helene Vitali (ORCID: https://orcid.org/0000-0003-2744-3701)
- Yiwei Jia (ORCID: https://orcid.org/0000-0002-5824-8821)
- Jean‐Baptiste Ledoux (ORCID: https://orcid.org/0000-0003-0447-5073)
- Jaime Barranco (ORCID: https://orcid.org/0009-0000-2918-9298)
- Mauro Leidi (ORCID: https://orcid.org/0009-0007-1249-158X)
- J Bastiaansen
Institutions
- University of Bern (CH)
- HES-SO University of Applied Sciences and Arts Western Switzerland (CH)
- University Hospital of Bern (CH)
- Centre Hospitalier Universitaire Vaudois (CH)
- Italian Institute of Technology (IT)
- HES-SO Valais-Wallis (CH)
- Centre d'Imagerie BioMedicale (CH)
- The Sense Innovation and Research Center (CH)
- University of Genoa (IT)
- University of Lausanne (CH)
Publication Details
- Journal
- STAR Protocols
- Published
- 2026-10-27
- DOI
- https://doi.org/10.1016/j.xpro.2026.104903
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Haute école Spécialisée de Suisse Occidentale