Bullous Cutaneous Amyloidosis as the Initial Manifestation of Multiple Myeloma: A Case Report

Bullous amyloidosis is a rare manifestation of systemic amyloidosis. There are no studies on the prevalence of this condition in the medical literature. Approximately one hundred case reports of the disease have been published, which justifies the need for more epidemiological data to study this condition. This article presents a case report of a patient with amyloid light-chain (AL) amyloidosis and multiple myeloma who developed hemorrhagic bullous lesions on the skin, compatible with the rare form of bullous amyloidosis.

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Publication Details

Journal
International Journal of Dermatology
Published
2026-10-26
DOI
https://doi.org/10.1111/ijd.70754
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Bullous Cutaneous Amyloidosis as the Initial Manifestation of Multiple Myeloma: A Case Report

Nílceo Schwery Michalany, Heron Fernando de Sousa Gonzaga, Amanda Carolina Zicatti da Silveira, Lucas de Castro Barroti et al.
International Journal of Dermatology
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Bullous Cutaneous Amyloidosis as the Initial Manifestation of Multiple Myeloma: A Case Report

Nílceo Schwery Michalany, Heron Fernando de Sousa Gonzaga, Amanda Carolina Zicatti da Silveira, Lucas de Castro Barroti, Henrique Proença, Mílvia Maria Simões e Silva Enokihara, Sérgio Henrique Hirata, João Pedro Mendes Silva Lega, Érika Thiemy B. Miyaguchi, Sergio Yamada
article en

Abstract

Bullous amyloidosis is a rare manifestation of systemic amyloidosis. There are no studies on the prevalence of this condition in the medical literature. Approximately one hundred case reports of the disease have been published, which justifies the need for more epidemiological data to study this condition. This article presents a case report of a patient with amyloid light-chain (AL) amyloidosis and multiple myeloma who developed hemorrhagic bullous lesions on the skin, compatible with the rare form of bullous amyloidosis.

International Journal of Dermatology
Universidade Federal de São Paulo (BR)
Openalex Percentile: Top 22%
Amyloidosis: Diagnosis, Treatment, Outcomes
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