Pachygyria and “Tigroid” White-matter Pattern in a Treated Case of Congenital Cytomegalovirus Infection

Abstract A 2-year-old girl with treated congenital cytomegalovirus infection presented with focal seizures. Brain magnetic resonance imaging (MRI) demonstrated frontal pachygyria and asymmetric “tigroid” white-matter abnormalities. These MRI findings represent delayed manifestation of antenatal cytomegalovirus-related brain injury rather than progressive disease, highlighting the importance of accurate radiologic recognition to avoid misdiagnosis.

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Publication Details

Journal
Journal of Pediatric Neurosciences
Published
2026-10-27
DOI
https://doi.org/10.4103/jpn.jpn_128_26
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
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article

Pachygyria and “Tigroid” White-matter Pattern in a Treated Case of Congenital Cytomegalovirus Infection

Ravindra Singh Jadon, Shaurya Pharasi, Sahil Singla
1 links
Journal of Pediatric Neurosciences
Cytomegalovirus and herpesvirus research
article

Pachygyria and “Tigroid” White-matter Pattern in a Treated Case of Congenital Cytomegalovirus Infection

Ravindra Singh Jadon, Shaurya Pharasi, Sahil Singla
article en

Abstract

Abstract A 2-year-old girl with treated congenital cytomegalovirus infection presented with focal seizures. Brain magnetic resonance imaging (MRI) demonstrated frontal pachygyria and asymmetric “tigroid” white-matter abnormalities. These MRI findings represent delayed manifestation of antenatal cytomegalovirus-related brain injury rather than progressive disease, highlighting the importance of accurate radiologic recognition to avoid misdiagnosis.

Journal of Pediatric Neurosciences
Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital (IN)
Good health and well-being
Openalex Percentile: Top 12%
Cytomegalovirus and herpesvirus research
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