Fast response in facial vitiligo monitored by non-invasive imaging during topical ruxolitinib treatment

Dear Editor, Vitiligo is a chronic autoimmune disorder affecting 0.5-1% of the population, characterized by progressive melanocyte loss and depigmented macules. Non-segmental vitiligo (NSV) is the most common subtype, typically involving the face and acral areas, with relevant psychosocial impact. Conventional therapies frequently provide delayed or incomplete responses. Recently, topical Janus kinase (JAK) inhibitors, such as ruxolitinib 1.5% cream, have shown promise in promoting repigmentation. [...].

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Publication Details

Journal
Dermatology Reports
Published
2026-10-27
DOI
https://doi.org/10.4081/dr.2026.10964
Primary Topic
melanin and skin pigmentation
Type
article
Field-Weighted Citation Impact
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Fast response in facial vitiligo monitored by non-invasive imaging during topical ruxolitinib treatment

Giovanni Pellacani, Annunziata Dattola, Francesca Paola Sasso, Maria Elisabetta Greco et al.
1 links
Dermatology Reports
melanin and skin pigmentation
article

Fast response in facial vitiligo monitored by non-invasive imaging during topical ruxolitinib treatment

Giovanni Pellacani, Annunziata Dattola, Francesca Paola Sasso, Maria Elisabetta Greco, Alberto di Caro, Steven Paul Nisticò, Francesca Feresin
article en

Abstract

Dear Editor, Vitiligo is a chronic autoimmune disorder affecting 0.5-1% of the population, characterized by progressive melanocyte loss and depigmented macules. Non-segmental vitiligo (NSV) is the most common subtype, typically involving the face and acral areas, with relevant psychosocial impact. Conventional therapies frequently provide delayed or incomplete responses. Recently, topical Janus kinase (JAK) inhibitors, such as ruxolitinib 1.5% cream, have shown promise in promoting repigmentation. [...].

Dermatology Reports
Sapienza University of Rome (IT)
Good health and well-being
Openalex Percentile: Top 16%
melanin and skin pigmentation
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