Animatistic Querying

Animatistic querying is a method of questioning a body of knowledge by instructing a large language model to speak as a non-human entity, such as a protein, a reagent or an object, and to describe its situation from that entity’s position. This short text defines the term, gives an example from cell-free protein synthesis (the enzyme DsbC, alone and in dialogue with glutathione), distinguishes the method from persona prompting and science-education role-play, states its main limit, and explains the choice of “animatistic” over “animistic.”

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-27
DOI
https://doi.org/10.5281/zenodo.23679279
Primary Topic
Science Education and Pedagogy
Type
preprint
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Animatistic Querying

Inger Le Gué
2 links
Zenodo (CERN European Organization for Nuclear Research)
Science Education and Pedagogy
preprint

Animatistic Querying

Inger Le Gué
preprint en

Abstract

Animatistic querying is a method of questioning a body of knowledge by instructing a large language model to speak as a non-human entity, such as a protein, a reagent or an object, and to describe its situation from that entity’s position. This short text defines the term, gives an example from cell-free protein synthesis (the enzyme DsbC, alone and in dialogue with glutathione), distinguishes the method from persona prompting and science-education role-play, states its main limit, and explains the choice of “animatistic” over “animistic.”

Zenodo (CERN European Organization for Nuclear Research)
Science Education and Pedagogy
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Animatistic Querying — Inger Le Gué · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS