Three-Dimensional Culture Reshapes Extracellular Vesicle Profiles as Revealed by Super-Resolution Nanoimaging, Next-Generation Sequencing, and Proteomic Analyses

Extracellular vesicles (EVs) are critical mediators of intercellular communication and promising cancer biomarkers; however, identifying EVs derived from specific tissues or cell

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Publication Details

Published
2026-10-26
DOI
https://doi.org/10.20517/scierxiv202610.0971.v1
Primary Topic
Extracellular vesicles in disease
Type
preprint

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preprint

Three-Dimensional Culture Reshapes Extracellular Vesicle Profiles as Revealed by Super-Resolution Nanoimaging, Next-Generation Sequencing, and Proteomic Analyses

Olivier D. Loudig, Megan I. Mitchell, Alexandre Kitching, Iddo Z. Ben‐Dov et al.
Extracellular vesicles in disease
preprint

Three-Dimensional Culture Reshapes Extracellular Vesicle Profiles as Revealed by Super-Resolution Nanoimaging, Next-Generation Sequencing, and Proteomic Analyses

Olivier D. Loudig, Megan I. Mitchell, Alexandre Kitching, Iddo Z. Ben‐Dov, Alexander Spark, Vamsikrishna R. Vaidyula, Megan Mitchell, Elizabeth Pinsky, Erik DeJonge, Junfeng Ma, Christina Liu
preprint en

Abstract

Extracellular vesicles (EVs) are critical mediators of intercellular communication and promising cancer biomarkers; however, identifying EVs derived from specific tissues or cell

Drew University (US), Georgetown University (US), University of Skövde (SE), Hadassah Medical Center (IL), Georgetown University Medical Center (US), ZeptoMetrix (United States) (US), Hackensack Meridian Health (US)
National Institutes of Health
Extracellular vesicles in disease
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