Genetic Heterogeneity of Asthma Across Sex, Age at Onset, and Disease Severity

Summary Asthma genetic architecture varies according to age at onset and biological sex. Medication‐defined severity showed limited common variant genetic heterogeneity compared with age at onset and sex.

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Publication Details

Journal
Clinical & Experimental Allergy
Published
2026-10-26
DOI
https://doi.org/10.1111/cea.70466
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Genetic Heterogeneity of Asthma Across Sex, Age at Onset, and Disease Severity

Patricia Silveyra, Eugene R. Bleecker, Maria Kyriakidou, Joe Zein et al.
Clinical & Experimental Allergy
Asthma and respiratory diseases
article

Genetic Heterogeneity of Asthma Across Sex, Age at Onset, and Disease Severity

Patricia Silveyra, Eugene R. Bleecker, Maria Kyriakidou, Joe Zein, Deborah A. Meyers, Benjamin M Gaston, Juliana M. Kling, Victor E. Ortega, Shiwani Keswani, Lacey Nixon, G Fernandez, Xianfeng Chen, Bo Hu
article en

Abstract

Summary Asthma genetic architecture varies according to age at onset and biological sex. Medication‐defined severity showed limited common variant genetic heterogeneity compared with age at onset and sex.

Clinical & Experimental Allergy
Indiana University Health (US), Mayo Clinic (US), Duke University (US), Riley Hospital for Children (US), Indiana University Bloomington (US), Mayo Clinic in Arizona (US), Indiana University (US)
National Institutes of Health, National Heart, Lung, and Blood Institute
Openalex Percentile: Top 13%
Asthma and respiratory diseases
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Genetic Heterogeneity of Asthma Across Sex, Age at Onset, and Disease Severity — Patricia Silveyra, Eugene R. Bleecker, et al. · Clinical & Experimental Allergy (2026) | TGRS Research Map | TGRS