Efficacy and safety of trans-fornix conjunctival retrobulbar block in a prospective randomized controlled trial
Retrobulbar block is widely used for vitreoretinal surgery, but the conventional transcutaneous technique advances a sharp needle blindly through the lower eyelid. We evaluated a trans -fornix conjunctival approach in which a curved blunt-tip needle is advanced into the muscle cone under the operating microscope. In a two-center randomized trial, 196 patients were stratified by expected surgical duration and allocated to the transcutaneous or the trans -fornix technique, and pain was graded at predefined procedural stages. The trans -fornix approach reduced pain during anesthetic injection in both cohorts and during scleral indentation in longer procedures, and fewer patients required supplemental anesthesia. Ocular akinesia was better with the trans -fornix technique, and periorbital hemorrhage and ecchymosis occurred only in the transcutaneous group. These findings support the trans -fornix block as a practical and reproducible option for regional anesthesia in vitreoretinal surgery.
Authors
- Tao Xu (ORCID: https://orcid.org/0000-0002-8260-9754)
- Kejun Liu
- Chunyan Xi
- Ruibo Chen
- Guorong Shi
- Mengqing Yin
- Kai Hu
- Ruirui Chen
- Bing Chen
- Chunming Chen
Institutions
- Xiamen University (CN)
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Nanjing Drum Tower Hospital (CN)
- He Eye Hospital (CN)
- Southeast University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- iScience
- Published
- 2026-10-26
- DOI
- https://doi.org/10.1016/j.isci.2026.118026
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00