HLA allele DRB1*01:03: the genetic link to neutralizing IL-10 antibodies in inflammatory bowel disease
In a recent study published in the New England Journal of Medicine , Gharahdaghi and colleagues link the HLA allele DRB1*01:03 to interleukin-10 (IL-10) neutralizing autoantibodies in a cohort of patients with inflammatory bowel disease (IBD). 1
Authors
- Jochen Mattner (ORCID: https://orcid.org/0000-0003-2254-6664)
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Universitätsklinikum Erlangen (DE)
Publication Details
- Journal
- Signal Transduction and Targeted Therapy
- Published
- 2026-10-26
- DOI
- https://doi.org/10.1038/s41392-026-03005-8
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- Staedtler Stiftung
- Chinesisch-Deutsche Zentrum für Wissenschaftsförderung
- Universitätsklinikum Erlangen