Vehicle Optimization of Topical Clobetasol Propionate in Disseminated Granuloma Annulare: Clinical Insights From Two Cases
Vehicle composition may influence topical corticosteroid performance. In two patients with disseminated granuloma annulare, switching from clobetasol ointment to the same-strength solution in diethylene glycol monoethyl ether (DEGEE) was followed by complete clearance, suggesting formulation optimization may be considered when topical treatment provides an inadequate response.
Authors
- Vincenzo Scarano (ORCID: https://orcid.org/0000-0003-3503-7156)
- Gerardo Cazzato (ORCID: https://orcid.org/0000-0003-0325-4316)
- Giulia Ciccarese (ORCID: https://orcid.org/0000-0001-8363-0195)
- Alexandre Raphael Meduri (ORCID: https://orcid.org/0009-0009-4992-6764)
- Giorgia Sbarra
- Francesca Ambrogio (ORCID: https://orcid.org/0000-0001-5718-7003)
- Caterina Foti (ORCID: https://orcid.org/0000-0001-6196-9788)
- William Andrew Rosato (ORCID: https://orcid.org/0009-0003-3500-1978)
- Paolo Antonio Danza (ORCID: https://orcid.org/0009-0003-0808-2960)
- Giuseppe Demichele (ORCID: https://orcid.org/0009-0000-6993-3392)
- Mario Della Mura (ORCID: https://orcid.org/0009-0009-5116-2484)
Institutions
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2026-10-26
- DOI
- https://doi.org/10.1002/ccr3.73794
- Primary Topic
- Skin Diseases and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00