Therapeutic delivery systems need to focus on cellular precision to target neurodegeneration

The central problem when delivering drugs to the brain is no longer crossing the blood-brain barrier, but delivering therapeutics to the right cells, in the right regions to target neurodegeneration, within a dynamically changing neurovascular unit.

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Publication Details

Journal
PLoS Biology
Published
2026-10-26
DOI
https://doi.org/10.1371/journal.pbio.3004049
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
0.00

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article

Therapeutic delivery systems need to focus on cellular precision to target neurodegeneration

Ebru Ercan-Herbst, Sinem Ağılkaya, Kim Susann Keller, Lavanya Gupta
PLoS Biology
Nanoparticle-Based Drug Delivery
article

Therapeutic delivery systems need to focus on cellular precision to target neurodegeneration

Ebru Ercan-Herbst, Sinem Ağılkaya, Kim Susann Keller, Lavanya Gupta
article en

Abstract

The central problem when delivering drugs to the brain is no longer crossing the blood-brain barrier, but delivering therapeutics to the right cells, in the right regions to target neurodegeneration, within a dynamically changing neurovascular unit.

PLoS BiologyVol. 24(10)
Reutlingen University (DE)
Carl-Zeiss-Stiftung, Bundesministerium für Bildung und Forschung
Openalex Percentile: Top 28%
Nanoparticle-Based Drug Delivery
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