Tailoring Pain Self‑management for Chronic Pain and Opioid Use Disorder: Qualitative Insights from Patients and Clinicians
BACKGROUND: Chronic pain, opioid use disorder (OUD), and opioid misuse (OM) often appear as co-occurring conditions; however, they are infrequently treated simultaneously which may lead to worse health outcomes. A novel way to manage these co-occurring conditions is by using a pain self-management (PSM) approach, which focuses on changing behavior through mechanisms that focus on self-regulation. Behavioral interventions, such as PSM, are a safe and effective approach to chronic pain treatment and have the highest likelihood of impact when they are tailored to the target population and setting. OBJECTIVE: The purpose of this study was to determine how to tailor PSM for patients with co-occurring chronic pain and OUD/OM. DESIGN: Qualitative study, pragmatic clinical trial. PARTICIPANTS: Patients with chronic pain and OUD/OM (N = 31) and clinicians/staff (N = 15) from primary care settings in Pennsylvania and West Virginia were interviewed to gather information needed to develop and tailor a PSM intervention. INTERVENTIONS: Pain self-management. APPROACH: Interviews were predominantly conducted remotely and addressed thoughts about pain, pain management, and the usefulness of behavioral interventions. Interviews were transcribed verbatim and coded using an inductively developed codebook; upon completion of coding, conventional content and thematic analysis was conducted. KEY RESULTS: Results of participant interviews included key takeaways such as the risks of long-term opioid therapy, lack of pain self-efficacy, and the complex patient-provider relationships that arise during treatment of these co-occurring conditions. Clinicians/staff interviews discussed social determinants of health and stigma that can hinder clinicians from providing proper care. CONCLUSIONS: The qualitative findings described from this pragmatic clinical trial allowed for the precise formulation of a PSM intervention that specifically targets patients with chronic pain and OUD/OM and may be relevant to the future development of other psychosocial-based interventions.
Authors
- Lyn Yuen Choo (ORCID: https://orcid.org/0000-0001-5640-0749)
- Ramona Emerson
- Lane Alexander
- Megan Hamm (ORCID: https://orcid.org/0000-0002-7842-5290)
- Karlyn A. Edwards (ORCID: https://orcid.org/0000-0002-5821-3733)
- Jessica S. Merlin (ORCID: https://orcid.org/0000-0003-3207-4875)
- Erin L. Winstanley (ORCID: https://orcid.org/0000-0003-3571-0259)
- Samantha Nash (ORCID: https://orcid.org/0000-0003-3772-5614)
- Flor de Abril Cameron (ORCID: https://orcid.org/0000-0002-4079-4744)
- Promiti Debi
- Edna J Evington
- Melessa Salay
Institutions
- University of Pittsburgh (US)
- University of Houston (US)
- The Ohio State University (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of General Internal Medicine
- Published
- 2026-10-26
- DOI
- https://doi.org/10.1007/s11606-026-10927-0
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00