American Epilepsy Society/Congress of Neurological Surgeons Epilepsy Surgery Clinical Practice Guideline

This practice guideline from the American Epilepsy Society and the Congress of Neurological Surgeons provides evidence-based recommendations for surgical treatment of epilepsy for adults and children. It is an update to previous practice parameters published by the Academy of Neurology in 2003. The multidisciplinary panel addressed resective procedures for mesial temporal epilepsy, neocortical epilepsy, and resection/disconnection of hypothalamic hamartoma. It also examined evidence for callosotomy in developmental and epileptic encephalopathies. It did not intentionally address neurostimulation treatment. A comprehensive literature review was conducted using Grading of Recommendations Assessment, Development, and Education methodology, and it was also used for decision making. This guideline considers not only seizure outcomes but also other critical and important outcomes. Seizures, quality of life, mortality, adverse events, and verbal memory loss were considered critical outcomes, whereas other neuropsychological deficits besides verbal memory loss (ie, naming, fluency), neuropsychiatric, and social outcomes were considered important outcomes.

Authors

Institutions

Publication Details

Journal
Neurosurgery
Published
2026-10-26
DOI
https://doi.org/10.1227/neu.0000000000004254
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

American Epilepsy Society/Congress of Neurological Surgeons Epilepsy Surgery Clinical Practice Guideline

Taylor Duda, Mei Bou Nasif, Melissa Lannon, Shannon Hart et al.
Neurosurgery
Epilepsy research and treatment
article

American Epilepsy Society/Congress of Neurological Surgeons Epilepsy Surgery Clinical Practice Guideline

Taylor Duda, Mei Bou Nasif, Melissa Lannon, Shannon Hart, Robert A. McGovern, Shawna L Strickland, Barbara C. Jobst, Mohamad Ali Kesserwan, Angela V. Price, Robyn M. Busch, Amanda Martyniuk, Golbarg T. Saber, John David Rolston, Jorge González-Martínez, Howard L. Weiner, Dennis D. Spencer, Alexandra Eid, Andrea J. Darzi, Guy M. McKhann, Gregory Kent Bergey, Jennifer L. Hopp, Aatif M. Husain, James L. Bernat, David S. Gloss, Douglas R. Nordli, Christopher Saouda, Victoria Vinarsky, Dina Ghandour, David Bauer, Sunjay Sharma, Jerome Engel, Yetiani M. Roldán-Benítez
article en

Abstract

This practice guideline from the American Epilepsy Society and the Congress of Neurological Surgeons provides evidence-based recommendations for surgical treatment of epilepsy for adults and children. It is an update to previous practice parameters published by the Academy of Neurology in 2003. The multidisciplinary panel addressed resective procedures for mesial temporal epilepsy, neocortical epilepsy, and resection/disconnection of hypothalamic hamartoma. It also examined evidence for callosotomy in developmental and epileptic encephalopathies. It did not intentionally address neurostimulation treatment. A comprehensive literature review was conducted using Grading of Recommendations Assessment, Development, and Education methodology, and it was also used for decision making. This guideline considers not only seizure outcomes but also other critical and important outcomes. Seizures, quality of life, mortality, adverse events, and verbal memory loss were considered critical outcomes, whereas other neuropsychological deficits besides verbal memory loss (ie, naming, fluency), neuropsychiatric, and social outcomes were considered important outcomes.

Neurosurgery
Dartmouth College (US), Northwestern University (US), Dartmouth Institute for Health Policy and Clinical Practice (US), University of Maryland, Baltimore (US), University of Minnesota (US), Cleveland Clinic (US), Harvard University (US), Johns Hopkins University (US), University of California, Los Angeles (US), University of Pittsburgh (US), Baylor College of Medicine (US), George Washington University (US), Columbia University Irving Medical Center (US), Johns Hopkins Medicine (US), Ronald Reagan UCLA Medical Center (US), UCLA Medical Center (US), University of Alabama at Birmingham (US), Yale University (US), University of Chicago (US), NeuroMedical Center (US), American Epilepsy Society (US), Dartmouth Psychiatric Research Center (US), Duke Medical Center (US), Olive View-UCLA Medical Center (US), The Neurological Institute (US), Dartmouth Health (US), Mass General Brigham (US), Rush University (US), The University of Texas Southwestern Medical Center (US), McMaster University (CA)
American Epilepsy Society, Congress of Neurological Surgeons
Openalex Percentile: Top 12%
Epilepsy research and treatment
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon