A decade-long device–valve interaction: severe aortic regurgitation after residual ventricular septal defect closure

A NTI1008"49-year-old woman underwent tetralogy of Fallot repair at age 16, including closure of a 25 mm intracristal ventricular septal defect (VSD) and right ventricular outflow tract reconstruction. Sixteen years later, a postoperative residual VSD was closed transcatheterly. Eleven years after device implantation, echocardiography showed mild-to-moderate aortic regurgitation (AR), which progressed to severe over 2 years, while the ascending aortic diameter increased from 38 to 45 mm despite 6-month surveillance. At the current admission, three-dimensional transoesophageal echocardiography showed the occluder impinging on the non-coronary and right coronary cusps at the commissure, restricting cusp motion and producing severe AR on colour Doppler (Panel A). Computed tomography confirmed protrusion into the aortic valve complex (Panel B). At surgery, both cusps were markedly thickened and firmly adherent to the occluder at the commissure (Panel C). The protruding portion of the device and adherent cusp tissue were excised (Panel D), followed by mechanical aortic valve replacement (Panel E). Recovery was uneventful, with normal prosthetic function at 1 month.

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Publication Details

Journal
European Heart Journal
Published
2026-10-24
DOI
https://doi.org/10.1093/eurheartj/ehag862
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

A decade-long device–valve interaction: severe aortic regurgitation after residual ventricular septal defect closure

Hongyan Liu, Zhengdong Hua, Rong Zhou
European Heart Journal
Congenital Heart Disease Studies
article

A decade-long device–valve interaction: severe aortic regurgitation after residual ventricular septal defect closure

Hongyan Liu, Zhengdong Hua, Rong Zhou
article en

Abstract

A NTI1008"49-year-old woman underwent tetralogy of Fallot repair at age 16, including closure of a 25 mm intracristal ventricular septal defect (VSD) and right ventricular outflow tract reconstruction. Sixteen years later, a postoperative residual VSD was closed transcatheterly. Eleven years after device implantation, echocardiography showed mild-to-moderate aortic regurgitation (AR), which progressed to severe over 2 years, while the ascending aortic diameter increased from 38 to 45 mm despite 6-month surveillance. At the current admission, three-dimensional transoesophageal echocardiography showed the occluder impinging on the non-coronary and right coronary cusps at the commissure, restricting cusp motion and producing severe AR on colour Doppler (Panel A). Computed tomography confirmed protrusion into the aortic valve complex (Panel B). At surgery, both cusps were markedly thickened and firmly adherent to the occluder at the commissure (Panel C). The protruding portion of the device and adherent cusp tissue were excised (Panel D), followed by mechanical aortic valve replacement (Panel E). Recovery was uneventful, with normal prosthetic function at 1 month.

European Heart Journal
Wuhan University (CN), Wuhan Asia Heart Hospital (CN)
Openalex Percentile: Top 12%
Congenital Heart Disease Studies
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A decade-long device–valve interaction: severe aortic regurgitation after residual ventricular septal defect closure — Hongyan Liu, Zhengdong Hua, et al. · European Heart Journal (2026) | TGRS Research Map | TGRS