Effects of Cosmetic Procedures Incorporating a Phytic Acid Complex and a Customized At-Home Skincare Routine on Facial Skin Aging: A Single-Patient Case Report

Background: Skin aging processes impair biochemical, structural, and physical properties, leading not only to aesthetic changes but also to the impairment of skin barrier functions. Although the biological efficacy of isolated phytic acid is well documented, the scientific literature lacks data on its effects within specific synergistic complexes. The aim of this study was to evaluate the potential effects of a phytic acid complex combined with a customized at-home skincare routine on facial skin aging, utilizing a single-patient case as an illustrative example of these synergistic mechanisms. Methods: A case study was conducted on a 48-year-old woman with facial skin aging and photoaged concerns. The treatment protocol comprised 6 treatments, performed every 7–10 days, using a phytic acid complex (20% phytic acid, 10% glycolic acid, 1% salicylic acid, 1% mandelic acid, and 2% kojic acid; pH 4.5), alongside an individualized home-care routine. Changes in skin parameters (wrinkle depth, hydration levels, hyperpigmentation, and keratinization) were evaluated using non-invasive instrumental diagnostic methods prior to each procedure and 7 days after the final treatment. A structured daily log was implemented to ensure adherence to the customized at-home skincare routine and to track self-reported observations. Results: Following the course of treatment, an objectively verified improvement in skin condition was observed in this specific case. A 20.5% reduction in wrinkle depth was recorded, along with a strong humectant effect: skin hydration levels increased by 28.3% in the T-zone and 41.9% in the U-zone. Furthermore, a 39.6% decrease in hyperpigmentation intensity and an 85% reduction in surface keratinization levels were observed. The subject’s self-assessment correlated with the instrumental diagnostic data; no adverse long-term inflammatory reactions or skin barrier impairments were reported. Conclusions: A course of cosmetic procedures using a phytic acid complex, combined with a customized at-home skincare routine, showed positive structural and functional improvements in aging facial skin by stimulating epidermal regeneration and reducing manifestations of melanogenesis. Due to the illustrative nature of this single-patient case study, the generalizability of these findings is limited. Although these preliminary results highlight promising clinical potential, further randomized controlled trials with larger sample sizes are required to validate these findings across broader populations.

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Publication Details

Journal
Dermato
Published
2026-10-22
DOI
https://doi.org/10.3390/dermato6040039
Primary Topic
Skin Protection and Aging
Type
article
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article

Effects of Cosmetic Procedures Incorporating a Phytic Acid Complex and a Customized At-Home Skincare Routine on Facial Skin Aging: A Single-Patient Case Report

Austėja Diržaitė, Rasa Krasauskė, Eva Šarlota Venckutė
Dermato
Skin Protection and Aging
article

Effects of Cosmetic Procedures Incorporating a Phytic Acid Complex and a Customized At-Home Skincare Routine on Facial Skin Aging: A Single-Patient Case Report

Austėja Diržaitė, Rasa Krasauskė, Eva Šarlota Venckutė
article en

Abstract

Background: Skin aging processes impair biochemical, structural, and physical properties, leading not only to aesthetic changes but also to the impairment of skin barrier functions. Although the biological efficacy of isolated phytic acid is well documented, the scientific literature lacks data on its effects within specific synergistic complexes. The aim of this study was to evaluate the potential effects of a phytic acid complex combined with a customized at-home skincare routine on facial skin aging, utilizing a single-patient case as an illustrative example of these synergistic mechanisms. Methods: A case study was conducted on a 48-year-old woman with facial skin aging and photoaged concerns. The treatment protocol comprised 6 treatments, performed every 7–10 days, using a phytic acid complex (20% phytic acid, 10% glycolic acid, 1% salicylic acid, 1% mandelic acid, and 2% kojic acid; pH 4.5), alongside an individualized home-care routine. Changes in skin parameters (wrinkle depth, hydration levels, hyperpigmentation, and keratinization) were evaluated using non-invasive instrumental diagnostic methods prior to each procedure and 7 days after the final treatment. A structured daily log was implemented to ensure adherence to the customized at-home skincare routine and to track self-reported observations. Results: Following the course of treatment, an objectively verified improvement in skin condition was observed in this specific case. A 20.5% reduction in wrinkle depth was recorded, along with a strong humectant effect: skin hydration levels increased by 28.3% in the T-zone and 41.9% in the U-zone. Furthermore, a 39.6% decrease in hyperpigmentation intensity and an 85% reduction in surface keratinization levels were observed. The subject’s self-assessment correlated with the instrumental diagnostic data; no adverse long-term inflammatory reactions or skin barrier impairments were reported. Conclusions: A course of cosmetic procedures using a phytic acid complex, combined with a customized at-home skincare routine, showed positive structural and functional improvements in aging facial skin by stimulating epidermal regeneration and reducing manifestations of melanogenesis. Due to the illustrative nature of this single-patient case study, the generalizability of these findings is limited. Although these preliminary results highlight promising clinical potential, further randomized controlled trials with larger sample sizes are required to validate these findings across broader populations.

DermatoVol. 6(4)
SMK University of Applied Social Sciences (LT), Lithuania Business University of Applied Science (LT)
Openalex Percentile: Top 10%
Skin Protection and Aging
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