Solitary Jejunal Hamartomatous Polyp Causing Intussusception in an Infant: A Case Report and Literature Review

Abstract Hamartomatous polyps of the small intestine are exceptionally rare in early infancy and are usually linked to syndromic conditions. Isolated lesions are uncommon, and jejunal involvement is particularly unusual. We describe a 4-month-old infant who presented with bilious vomiting, intermittent abdominal distension and melena. Imaging suggested intussusception, and surgery confirmed a jejunojejunal intussusception caused by a solitary intraluminal polyp serving as the lead point. Segmental resection with primary anastomosis was undertaken, and histopathology revealed a hamartomatous polyp without features of Peutz–Jeghers syndrome. This case emphasises that solitary hamartomatous polyps should be considered among the rare pathological lead points in infantile intussusception. Prompt surgical management is essential for favourable outcomes, and careful followup is recommended due to the potential for late emergence of syndromic associations.