Novel Fused Bicyclic Compounds as VRK1 Inhibitors for Treating Glioblastoma or Neuroblastoma
Abstract Provided herein are novel fused bicyclic compounds as VRK1 inhibitors, pharmaceutical compositions, use of such compounds in treating glioblastoma or neuroblastoma, and processes for preparing such compounds.
Authors
- Ram W. Sabnis (ORCID: https://orcid.org/0000-0001-7289-0581)
- Anika R. Sabnis (ORCID: https://orcid.org/0009-0008-9940-6583)
Institutions
- Mayo Clinic (US)
Publication Details
- Journal
- ACS Medicinal Chemistry Letters
- Published
- 2026-10-22
- DOI
- https://doi.org/10.1021/acsmedchemlett.6c00557
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00