Short- and Mid-Term Clinical, Functional, and Radiographic Outcomes of the 5C® MEDic Knee System Following Primary Total Knee Arthroplasty

Background Medial pivot total knee arthroplasty (TKA) has been developed to better reproduce native knee kinematics and improve patient satisfaction compared with conventional implant designs. This study evaluated the short- and mid-term clinical, functional, radiographic, and survivorship outcomes of the 5C® MEDic medial pivot knee system following primary TKA. Methods A retrospective cohort study included 419 primary TKAs performed in 372 patients between 2022 and 2025, with a minimum follow-up of 12 months. Clinical outcomes were assessed using the Knee injury and Osteoarthritis Outcome Score (KOOS-12), Oxford Knee Score (OKS), Forgotten Joint Score (FJS-12), visual analogue scale (VAS) satisfaction, and range of motion. Radiographic evaluation included hip–knee–ankle angle, arithmetic HKA, joint line obliquity, lateral distal femoral angle, medial proximal tibial angle, and Coronal Plane Alignment of the Knee (CPAK) classification. Implant survivorship was assessed using Kaplan–Meier analysis. Results Significant improvements were observed in all patient-reported outcome measures at 1 year . Mean OKS improved from 20.8 preoperatively to 41.2, while KOOS subscales demonstrated substantial gains in pain, symptoms, function, sports, and quality of life. Knee flexion increased from 111.1° to 123.2°, and extension improved from −5.6° to −0.7°. Kaplan–Meier survivorship was 99.8% at 1 year. One acute periprosthetic joint infection was successfully treated with debridement, antibiotics, and implant retention, and one patient developed deep venous thrombosis. No cases of aseptic loosening, instability, mechanical failure, or periprosthetic fracture were observed. Conclusions The 5C® MEDic medial pivot knee system demonstrated excellent early clinical, functional, and radiographic outcomes, high patient satisfaction, a low complication rate, and excellent short- and mid- term survivorship following primary TKA.