Extending synthetic medical education: generating OSCE cases with LLMs

Objective Structured Clinical Examinations (OSCEs) are central to competency-based medical education, yet high-quality case development is resource-intensive. Large language models (LLMs) offer a scalable solution, but comprehensive OSCE case generation, including components such as candidate instructions, standardized patient scripts, and examiner marking schemes, is underexplored. We developed an LLM-based tool to generate complete OSCE stations. Three board-certified internists evaluated 24 generated cases across eight internal medicine diagnoses and three learner levels using a 12-item Likert instrument. Ratings were high across all domains; communication behaviors (4.64/5), EPA alignment (4.62/5), and overall value (4.61/5) performed best; guideline concordance scored lowest (4.24/5) with the greatest rater disagreement. As a feasibility study, these findings establish that whole, schema-validated OSCE stations can be generated from a single structured call at a quality experts rate as acceptable, while also identifying guideline concordance and difficult calibration as the domains most requiring faculty oversight -- providing reproducible infrastructure for, but not yet evidence of, effective EPA-aligned OSCE development.

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Publication Details

Journal
npj Digital Medicine
Published
2026-10-19
DOI
https://doi.org/10.1038/s41746-026-03421-8
Primary Topic
Innovations in Medical Education
Type
article
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article

Extending synthetic medical education: generating OSCE cases with LLMs

David C. Whitehead, Andrew Cheung, Caroline P. Meehan, Marc D. Succi et al.
npj Digital Medicine
Innovations in Medical Education
article

Extending synthetic medical education: generating OSCE cases with LLMs

David C. Whitehead, Andrew Cheung, Caroline P. Meehan, Marc D. Succi, Arya S Rao, Ali Ebada, Kaiz P. Esmail, Richard S. Lee
article en

Abstract

Objective Structured Clinical Examinations (OSCEs) are central to competency-based medical education, yet high-quality case development is resource-intensive. Large language models (LLMs) offer a scalable solution, but comprehensive OSCE case generation, including components such as candidate instructions, standardized patient scripts, and examiner marking schemes, is underexplored. We developed an LLM-based tool to generate complete OSCE stations. Three board-certified internists evaluated 24 generated cases across eight internal medicine diagnoses and three learner levels using a 12-item Likert instrument. Ratings were high across all domains; communication behaviors (4.64/5), EPA alignment (4.62/5), and overall value (4.61/5) performed best; guideline concordance scored lowest (4.24/5) with the greatest rater disagreement. As a feasibility study, these findings establish that whole, schema-validated OSCE stations can be generated from a single structured call at a quality experts rate as acceptable, while also identifying guideline concordance and difficult calibration as the domains most requiring faculty oversight -- providing reproducible infrastructure for, but not yet evidence of, effective EPA-aligned OSCE development.

npj Digital Medicine
Harvard University (US), Massachusetts General Hospital (US), The University of Texas Southwestern Medical Center (US), McMaster University (CA)
Openalex Percentile: Top 10%
Innovations in Medical Education
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