Extending synthetic medical education: generating OSCE cases with LLMs
Objective Structured Clinical Examinations (OSCEs) are central to competency-based medical education, yet high-quality case development is resource-intensive. Large language models (LLMs) offer a scalable solution, but comprehensive OSCE case generation, including components such as candidate instructions, standardized patient scripts, and examiner marking schemes, is underexplored. We developed an LLM-based tool to generate complete OSCE stations. Three board-certified internists evaluated 24 generated cases across eight internal medicine diagnoses and three learner levels using a 12-item Likert instrument. Ratings were high across all domains; communication behaviors (4.64/5), EPA alignment (4.62/5), and overall value (4.61/5) performed best; guideline concordance scored lowest (4.24/5) with the greatest rater disagreement. As a feasibility study, these findings establish that whole, schema-validated OSCE stations can be generated from a single structured call at a quality experts rate as acceptable, while also identifying guideline concordance and difficult calibration as the domains most requiring faculty oversight -- providing reproducible infrastructure for, but not yet evidence of, effective EPA-aligned OSCE development.
Authors
- David C. Whitehead (ORCID: https://orcid.org/0000-0002-3132-5292)
- Andrew Cheung (ORCID: https://orcid.org/0000-0002-5876-3487)
- Caroline P. Meehan
- Marc D. Succi (ORCID: https://orcid.org/0000-0002-1518-3984)
- Arya S Rao (ORCID: https://orcid.org/0000-0003-3007-4812)
- Ali Ebada (ORCID: https://orcid.org/0009-0008-6870-0069)
- Kaiz P. Esmail
- Richard S. Lee
Institutions
- Harvard University (US)
- Massachusetts General Hospital (US)
- The University of Texas Southwestern Medical Center (US)
- McMaster University (CA)
Publication Details
- Journal
- npj Digital Medicine
- Published
- 2026-10-19
- DOI
- https://doi.org/10.1038/s41746-026-03421-8
- Primary Topic
- Innovations in Medical Education
- Type
- article
- Field-Weighted Citation Impact
- 0.00