Characterisation of musculoskeletal health problems encountered following critical illness and their relationship with physical function: a prospective observational study

Purpose Poor musculoskeletal (MSK) health is common following critical illness, negatively impacting quality of life. Holistic MSK assessment of critical care survivors has not previously been undertaken. The aim was to characterise MSK problems following critical illness and explore disability in patients with poor MSK health.Materials and methods A holistic MSK assessment was undertaken in participants six months after admission to intensive care. Participants with poor MSK health underwent an exploratory, functional assessment mirroring the domains of the International Classification of Functioning Disability and Health framework (ICF).Results Sixty-one participants underwent MSK assessment and 11 the functional assessment. Multisite problems (n = 33, 54.1%) and high levels of fear-avoidance related to physical activity (n = 15, 24.6%) were common. MSK health correlated with pain (p = 0.008), strength (p = 0.002), and fear-avoidance beliefs related to physical activity and work (p < 0.001). Participants with upper limb problems had high levels of disability with mean QuickDASH scores of 48.14 (SD24.49). Participants were sedentary for a median (IQR) of 21.7 h (20.5–22.1) per day.Conclusions Participants had high pain levels and experienced problems across all ICF domains. These results highlight an urgent need for research into targeted rehabilitation interventions to improve MSK health following critical illness.

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Publication Details

Journal
Disability and Rehabilitation
Published
2026-10-19
DOI
https://doi.org/10.1080/09638288.2026.2748408
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

Characterisation of musculoskeletal health problems encountered following critical illness and their relationship with physical function: a prospective observational study

Mark A. Williams, Helen Dawes, Owen D. Gustafson, Elizabeth King
Disability and Rehabilitation
Intensive Care Unit Cognitive Disorders
article

Characterisation of musculoskeletal health problems encountered following critical illness and their relationship with physical function: a prospective observational study

Mark A. Williams, Helen Dawes, Owen D. Gustafson, Elizabeth King
article en

Abstract

Purpose Poor musculoskeletal (MSK) health is common following critical illness, negatively impacting quality of life. Holistic MSK assessment of critical care survivors has not previously been undertaken. The aim was to characterise MSK problems following critical illness and explore disability in patients with poor MSK health.Materials and methods A holistic MSK assessment was undertaken in participants six months after admission to intensive care. Participants with poor MSK health underwent an exploratory, functional assessment mirroring the domains of the International Classification of Functioning Disability and Health framework (ICF).Results Sixty-one participants underwent MSK assessment and 11 the functional assessment. Multisite problems (n = 33, 54.1%) and high levels of fear-avoidance related to physical activity (n = 15, 24.6%) were common. MSK health correlated with pain (p = 0.008), strength (p = 0.002), and fear-avoidance beliefs related to physical activity and work (p < 0.001). Participants with upper limb problems had high levels of disability with mean QuickDASH scores of 48.14 (SD24.49). Participants were sedentary for a median (IQR) of 21.7 h (20.5–22.1) per day.Conclusions Participants had high pain levels and experienced problems across all ICF domains. These results highlight an urgent need for research into targeted rehabilitation interventions to improve MSK health following critical illness.

Disability and Rehabilitation
Oxford Brookes University (GB), NHS Blood and Transplant (GB), University of Exeter (GB), University of Oxford (GB), NIHR Exeter Clinical Research Facility (GB), Oxford University Hospitals NHS Trust (GB)
Openalex Percentile: Top 11%
Intensive Care Unit Cognitive Disorders
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