One health approach to rabies in India: bridging veterinary and medical systems to achieve zero by 2030

India carries close to a third of the global dog-mediated rabies burden [4,5] and has committed, through the National Action Plan for Dog-Mediated Rabies Elimination (NAPRE, 2021), to zero human deaths by 2030 [2,6]. This review asks why a country with a national plan, notifiable-disease status, domestic vaccine manufacturing and two documented state-level elimination successes still loses thousands of lives each year, and identifies the specific veterinary-medical interfaces that must be engineered before 2030. We synthesise the 2022-23 ICMR-NIE nationwide community survey [4,9], National Rabies Control Programme returns [6,8], WHO/WOAH/FAO guidance [1,2], national genomic surveillance [27,28], and elimination programmes from Goa [15], Sikkim [16], Bohol [17] and Latin America [18,19]. Modelled Indian mortality of 5,726 deaths annually exceeds the 54 suspected deaths notified in 2024 by roughly a hundredfold [4,8]. The binding constraint is architectural, not therapeutic. Four joints are broken: bite reports that never reach the veterinary sector, mass dog vaccination without a credible population denominator, post-mortem animal diagnosis concentrated in too few laboratories, and Integrated Bite Case Management (IBCM), which remains absent from NAPRE [6,20]. Whole-genome data showing predominant Arctic-like 1a circulation with state-level clustering indicate that transmission is largely local, that antigenic sites are conserved, and that district-scale elimination with traceable reintroduction is realistic [27,28]. Rabies elimination in India has become an integration problem rather than a scientific one. Seven measurable actions, each with a named owner and a 2030 indicator, would convert an adequate plan into a verifiable outcome [2,6].

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-18
DOI
https://doi.org/10.5281/zenodo.23447823
Primary Topic
Rabies epidemiology and control
Type
article
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article

One health approach to rabies in India: bridging veterinary and medical systems to achieve zero by 2030

Thirumurthi K., Mervin Kennady R.V., Priyanka R. and Sai Naga Vaishnavi
Zenodo (CERN European Organization for Nuclear Research)
Rabies epidemiology and control
article

One health approach to rabies in India: bridging veterinary and medical systems to achieve zero by 2030

Thirumurthi K., Mervin Kennady R.V., Priyanka R. and Sai Naga Vaishnavi
article en

Abstract

India carries close to a third of the global dog-mediated rabies burden [4,5] and has committed, through the National Action Plan for Dog-Mediated Rabies Elimination (NAPRE, 2021), to zero human deaths by 2030 [2,6]. This review asks why a country with a national plan, notifiable-disease status, domestic vaccine manufacturing and two documented state-level elimination successes still loses thousands of lives each year, and identifies the specific veterinary-medical interfaces that must be engineered before 2030. We synthesise the 2022-23 ICMR-NIE nationwide community survey [4,9], National Rabies Control Programme returns [6,8], WHO/WOAH/FAO guidance [1,2], national genomic surveillance [27,28], and elimination programmes from Goa [15], Sikkim [16], Bohol [17] and Latin America [18,19]. Modelled Indian mortality of 5,726 deaths annually exceeds the 54 suspected deaths notified in 2024 by roughly a hundredfold [4,8]. The binding constraint is architectural, not therapeutic. Four joints are broken: bite reports that never reach the veterinary sector, mass dog vaccination without a credible population denominator, post-mortem animal diagnosis concentrated in too few laboratories, and Integrated Bite Case Management (IBCM), which remains absent from NAPRE [6,20]. Whole-genome data showing predominant Arctic-like 1a circulation with state-level clustering indicate that transmission is largely local, that antigenic sites are conserved, and that district-scale elimination with traceable reintroduction is realistic [27,28]. Rabies elimination in India has become an integration problem rather than a scientific one. Seven measurable actions, each with a named owner and a 2030 indicator, would convert an adequate plan into a verifiable outcome [2,6].

Zenodo (CERN European Organization for Nuclear Research)
Openalex Percentile: Top 15%
Rabies epidemiology and control
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