Can AI Assistants Trigger Mental Illness in Users?

As conversational artificial intelligence models become ubiquitous fixtures in professional and personal workflows, the nature of human-tool interaction has the potential to gradually shift from mechanical utility to parasocial dependency. While existing literature frequently addresses adverse events related to data privacy, algorithmic bias, and intellectual deskilling, the pathopsychological sequelae of sustained AI integration remain largely unexamined. Here, we describe and preliminarily characterize the AI Assistant Syndrome, a human psychiatric construct encompassing acute chatbot-induced anxiety and mental exhaustion. This preliminary description will guide future systematic investigations to recognize, prevent, and treat this syndrome.

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Publication Details

Journal
F1000Research
Published
2026-10-17
DOI
https://doi.org/10.12688/f1000research.191633.1
Primary Topic
Technostress in Professional Settings
Type
article
Field-Weighted Citation Impact
0.00
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article

Can AI Assistants Trigger Mental Illness in Users?

Eleftherios P. Diamandis
F1000Research
Technostress in Professional Settings
article

Can AI Assistants Trigger Mental Illness in Users?

Eleftherios P. Diamandis
article en

Abstract

As conversational artificial intelligence models become ubiquitous fixtures in professional and personal workflows, the nature of human-tool interaction has the potential to gradually shift from mechanical utility to parasocial dependency. While existing literature frequently addresses adverse events related to data privacy, algorithmic bias, and intellectual deskilling, the pathopsychological sequelae of sustained AI integration remain largely unexamined. Here, we describe and preliminarily characterize the AI Assistant Syndrome, a human psychiatric construct encompassing acute chatbot-induced anxiety and mental exhaustion. This preliminary description will guide future systematic investigations to recognize, prevent, and treat this syndrome.

F1000ResearchVol. 15
Lunenfeld-Tanenbaum Research Institute (CA)
Good health and well-being
Openalex Percentile: Top 8%
Technostress in Professional Settings
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