Siglec Expression Patterns in Food Allergy Reveal Altered Intensity but Not Frequency

Summary Siglecs are diversely expressed among PBMCs, with the broadest expression on antigen‐presenting cells. Food‐allergic individuals with objective symptoms show lower relative expression of Siglecs compared to those with subjective symptoms.

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Publication Details

Journal
Clinical & Experimental Allergy
Published
2026-10-16
DOI
https://doi.org/10.1111/cea.70458
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00

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Siglec Expression Patterns in Food Allergy Reveal Altered Intensity but Not Frequency

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Siglec Expression Patterns in Food Allergy Reveal Altered Intensity but Not Frequency

Edward F. Knol, Kitty C. M. Verhoeckx, Anna M. Ehlers, André C. Knulst, J. S. H. Schaapherder, G. J. P. H. Boons
article en

Abstract

Summary Siglecs are diversely expressed among PBMCs, with the broadest expression on antigen‐presenting cells. Food‐allergic individuals with objective symptoms show lower relative expression of Siglecs compared to those with subjective symptoms.

Clinical & Experimental Allergy
University of Georgia (US), Utrecht University (NL), University Medical Center Utrecht (NL)
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Good health and well-being
Openalex Percentile: Top 15%
Food Allergy and Anaphylaxis Research
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