Feasibility of a Multimodal Lifestyle Intervention Programme for Patients With Ulcerative Colitis: A Single‐Arm Pilot Study

Plain Language Summary Lifestyle factors, such as exercise, diet and mental health, have shown promise in improving well‐being in people with ulcerative colitis, a chronic inflammatory condition of the large bowel. However, these factors are usually addressed separately in research. Therefore, we explored whether a 24‐week programme combining exercise, personalised dietary advice and psychological support could be implemented in people with ulcerative colitis. Thirty patients took part in the programme. Most participants remained in the study, and three‐quarters were satisfied with the programme. However, maintaining participation across the different components proved challenging. In particular, adherence to the exercise programme was low, whereas adherence to dietary advice was higher. More than half of the participants were eligible for psychological support, but only a quarter of those started the programme. No unexpected safety concerns were observed. Overall, our findings suggest that patients may be interested in a broad lifestyle approach, but that initial interest does not necessarily translate into sustained participation. Therefore, future programmes should focus on making lifestyle interventions more flexible, practical and tailored to individual people.