Decreasing Trends in Birth Prevalence and Severity of Cerebral Palsy in Sweden During 2000–2019: A Population‐Based Registry Study

AIM: To examine temporal trends in cerebral palsy (CP) birth prevalence and changes in functional severity in Sweden between 2000 and 2019. METHODS: This population-based registry study included all children with CP born in Sweden between 2000 and 2019. Annual CP birth prevalence was calculated using Poisson regression. Changes in functional severity were assessed using the Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS) levels across birth cohorts, with ordinal logistic regression used to examine their association. RESULTS: In total 4281 participants were included. CP birth prevalence decreased over the study period with a rate ratio per year of 0.985 (95% confidence interval 0.980-0.990) corresponding to a 1.5% annual reduction. The proportion of children with milder impairment increased over time. In crude analyses: children born in 2015-2019 had lower odds of higher MACS levels (OR 0.70, 95% CI 0.60-0.83, p ≤ 0.001), and GMFCS level (OR 0.77, 95% CI 0.65-0.92, p = 0.003) than those born in 2000-2004. CONCLUSION: CP birth prevalence in Sweden decreased significantly between 2000 and 2019. A shift toward milder functional impairment was observed in more recent birth cohorts and occurred alongside changes in CP subtype distribution.

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Publication Details

Journal
Acta Paediatrica
Published
2026-10-16
DOI
https://doi.org/10.1111/apa.70800
Primary Topic
Cerebral Palsy and Movement Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Decreasing Trends in Birth Prevalence and Severity of Cerebral Palsy in Sweden During 2000–2019: A Population‐Based Registry Study

Ann I. Alriksson‐Schmidt, Semhal Getachew Teka, Gunnar Hägglund
Acta Paediatrica
Cerebral Palsy and Movement Disorders
article

Decreasing Trends in Birth Prevalence and Severity of Cerebral Palsy in Sweden During 2000–2019: A Population‐Based Registry Study

Ann I. Alriksson‐Schmidt, Semhal Getachew Teka, Gunnar Hägglund
article en

Abstract

AIM: To examine temporal trends in cerebral palsy (CP) birth prevalence and changes in functional severity in Sweden between 2000 and 2019. METHODS: This population-based registry study included all children with CP born in Sweden between 2000 and 2019. Annual CP birth prevalence was calculated using Poisson regression. Changes in functional severity were assessed using the Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS) levels across birth cohorts, with ordinal logistic regression used to examine their association. RESULTS: In total 4281 participants were included. CP birth prevalence decreased over the study period with a rate ratio per year of 0.985 (95% confidence interval 0.980-0.990) corresponding to a 1.5% annual reduction. The proportion of children with milder impairment increased over time. In crude analyses: children born in 2015-2019 had lower odds of higher MACS levels (OR 0.70, 95% CI 0.60-0.83, p ≤ 0.001), and GMFCS level (OR 0.77, 95% CI 0.65-0.92, p = 0.003) than those born in 2000-2004. CONCLUSION: CP birth prevalence in Sweden decreased significantly between 2000 and 2019. A shift toward milder functional impairment was observed in more recent birth cohorts and occurred alongside changes in CP subtype distribution.

Acta Paediatrica
Lund University (SE), Skåne University Hospital (SE)
Stiftelsen för Bistånd åt Rörelsehindrade i Skåne, Vetenskapsrådet
Good health and well-being
Openalex Percentile: Top 13%
Cerebral Palsy and Movement Disorders
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