Plasma Resolvin D2 Is Elevated and Lipoxin A 4 Is Reduced in Atopic Dermatitis: A Candidate Lipid Mediator Imbalance
Summary Plasma lipid mediators are broadly suppressed in atopic dermatitis, except resolvin D2, which is elevated. Lipoxin A 4 is reduced in atopic dermatitis and warrants investigation as an anti‐inflammatory target.
Authors
- Yoshimi Miki (ORCID: https://orcid.org/0000-0002-8587-0333)
- Koremasa Hayama (ORCID: https://orcid.org/0000-0001-8651-2493)
- Shota Toyoshima (ORCID: https://orcid.org/0000-0002-3474-5743)
- Keisuke Shimizu (ORCID: https://orcid.org/0000-0003-1234-5789)
- Makoto Murakami (ORCID: https://orcid.org/0000-0002-4565-6017)
- Yoshitaka Taketomi (ORCID: https://orcid.org/0000-0003-4094-9846)
- Hideki Fujita (ORCID: https://orcid.org/0000-0001-8657-0618)
- Maho Tagui (ORCID: https://orcid.org/0000-0001-8152-6802)
- Yoshimichi Okayama (ORCID: https://orcid.org/0000-0001-5469-3541)
- Mana Ito
Institutions
- Nihon University (JP)
- Gumma Paz College (JP)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2026-10-15
- DOI
- https://doi.org/10.1111/cea.70455
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nihon University
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science and Technology
- Japan Society for the Promotion of Science