Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment

Abstract Achalasia is a rare esophageal motility disorder in children, often leading to delayed diagnosis. We report the first two pediatric cases treated with peroral endoscopic myotomy (POEM) at our center, both classified as type II achalasia and complicated by mucosal disease. A 15‐year‐old girl presented with progressive dysphagia and weight loss, diagnosed with type II achalasia and Candida esophagitis. A 13‐year‐old boy exhibited similar symptoms with a 27‐kg weight loss; histology revealed concurrent eosinophilic esophagitis. Both underwent successful POEM. These cases illustrate the clinical heterogeneity of pediatric achalasia and emphasize the importance of recognizing concomitant mucosal conditions that may delay diagnosis. POEM appears to be a safe and effective, minimally invasive treatment in the pediatric population, even in complex scenarios.

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Publication Details

Journal
JPGN Reports
Published
2026-10-15
DOI
https://doi.org/10.1002/jpr3.70260
Primary Topic
Gastroesophageal reflux and treatments
Type
article
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article

Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment

Fabio Rotondo, Antonio Marseglia, Anna Locatelli, Francesco Perri et al.
JPGN Reports
Gastroesophageal reflux and treatments
article

Two pediatric type II achalasia cases complicated by candidal and eosinophilic esophagitis: Successful peroral endoscopic myotomy treatment

Fabio Rotondo, Antonio Marseglia, Anna Locatelli, Francesco Perri, Maria Rosa Pastore, Massimo Pettoello Mantovani, Dalila Tedeschi, Marco Gentile
article en

Abstract

Abstract Achalasia is a rare esophageal motility disorder in children, often leading to delayed diagnosis. We report the first two pediatric cases treated with peroral endoscopic myotomy (POEM) at our center, both classified as type II achalasia and complicated by mucosal disease. A 15‐year‐old girl presented with progressive dysphagia and weight loss, diagnosed with type II achalasia and Candida esophagitis. A 13‐year‐old boy exhibited similar symptoms with a 27‐kg weight loss; histology revealed concurrent eosinophilic esophagitis. Both underwent successful POEM. These cases illustrate the clinical heterogeneity of pediatric achalasia and emphasize the importance of recognizing concomitant mucosal conditions that may delay diagnosis. POEM appears to be a safe and effective, minimally invasive treatment in the pediatric population, even in complex scenarios.

JPGN Reports
University of Foggia (IT), Casa Sollievo della Sofferenza (IT)
Good health and well-being
Openalex Percentile: Top 10%
Gastroesophageal reflux and treatments
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