A Bibliometric Analysis of Research Interest in Dupilumab for Chronic Rhinosinusitis With Nasal Polyposis

OBJECTIVE: The objective was to evaluate the rapid progress and interest regarding the role of dupilumab in the treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP). METHODOLOGY: The Web of Science Core Collection database was queried in a single day for publications using terms "dupilumab" and a combination of "chronic sinusitis," "rhinosinusitis," and "polyposis" without time restrictions. Document type, years, authors, countries with economic estimates, institutions, journal information, and keywords were analyzed and visualized using VOSviewer. Only original investigation and review articles were included for analysis. Further analysis of the top 10 cited articles were performed. RESULTS: (n = 17). B Claus was the most cited author pertaining to this topic, and the most frequent keywords and concepts spanned outcomes, immunology, allergy, and adverse events. CONCLUSION: Research regarding the use of dupilumab in the treatment of CRSwNP is rapidly evolving, highlighting the paradigm shift in treatment with the introduction of biologic therapy. This analysis showcased global interest in this topic, highlighting hallmark publications and prolific investigators, while also identifying areas for further exploration and collaboration.