Current status of genetic engineering for sophorolipids production

and others, could be a powerful tool to improve various aspects of sophorolipids production, including sophorolipids: titers, yields, productivities, novel forms, product selectivity, improved utilization of novel or sustainable fermentation feedstocks, process scalability, and process intensification. This review is designed to provide a focused look at the current status of genetic engineering for sophorolipids production, including assessments of notable studies on the generation of recombinant sophorolipid producers, their specific aims and achievements, as well as their associated challenges and knowledge gaps to be addressed. Additionally, further discussions on how the genetic engineering toolbox and physiological understandings of sophorolipid producers need to be further improved are also provided. The perspectives, discussions, and recommendations provided should aid future research and development endeavors to further improve the genetic engineering of sophorolipids producers, sophorolipids bioprocess development, and their further commercialization.

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Publication Details

Journal
Critical Reviews in Biotechnology
Published
2026-10-15
DOI
https://doi.org/10.1080/07388551.2026.2722957
Primary Topic
Microbial Metabolic Engineering and Bioproduction
Type
article
Field-Weighted Citation Impact
0.00

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article

Current status of genetic engineering for sophorolipids production

Robin Hoeven, James Benjamin Winterburn, Federico Visinoni, Phavit Wongsirichot et al.
Critical Reviews in Biotechnology
Microbial Metabolic Engineering and Bioproduction
article

Current status of genetic engineering for sophorolipids production

Robin Hoeven, James Benjamin Winterburn, Federico Visinoni, Phavit Wongsirichot, Roger Romero Jimenez, Javier Gomez Cardozo, Gerard Cloke Browne, Rebecca Dunn, Eve Rosser, Peter Martin
article en

Abstract

and others, could be a powerful tool to improve various aspects of sophorolipids production, including sophorolipids: titers, yields, productivities, novel forms, product selectivity, improved utilization of novel or sustainable fermentation feedstocks, process scalability, and process intensification. This review is designed to provide a focused look at the current status of genetic engineering for sophorolipids production, including assessments of notable studies on the generation of recombinant sophorolipid producers, their specific aims and achievements, as well as their associated challenges and knowledge gaps to be addressed. Additionally, further discussions on how the genetic engineering toolbox and physiological understandings of sophorolipid producers need to be further improved are also provided. The perspectives, discussions, and recommendations provided should aid future research and development endeavors to further improve the genetic engineering of sophorolipids producers, sophorolipids bioprocess development, and their further commercialization.

Critical Reviews in Biotechnology
University of Manchester (GB)
Engineering and Physical Sciences Research Council, Biotechnology and Biological Sciences Research Council
Zero hunger
Openalex Percentile: Top 24%
Microbial Metabolic Engineering and Bioproduction
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