A Case of Concurrent Antiacetylcholine Receptor-Positive Myasthenia Gravis and Anti-HMGCR–Positive Myositis Following Statin Exposure

Myasthenia gravis (MG) and inflammatory myopathy (IM) are distinct autoimmune diseases that rarely coexist. By 2020, fewer than 70 cases of MG-IM overlap had been reported, most with thymic abnormalities.1 MG-IM overlap has also been recognized as an immune-related adverse event from immune checkpoint inhibitor therapy.2

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Publication Details

Journal
The Journal of Rheumatology
Published
2026-10-15
DOI
https://doi.org/10.3899/jrheum.2025-0711
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00

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article

A Case of Concurrent Antiacetylcholine Receptor-Positive Myasthenia Gravis and Anti-HMGCR–Positive Myositis Following Statin Exposure

Andrew Lee Mammen, David W. Newton, Candie Jammal, Calvin Chen
The Journal of Rheumatology
Myasthenia Gravis and Thymoma
article

A Case of Concurrent Antiacetylcholine Receptor-Positive Myasthenia Gravis and Anti-HMGCR–Positive Myositis Following Statin Exposure

Andrew Lee Mammen, David W. Newton, Candie Jammal, Calvin Chen
article en

Abstract

Myasthenia gravis (MG) and inflammatory myopathy (IM) are distinct autoimmune diseases that rarely coexist. By 2020, fewer than 70 cases of MG-IM overlap had been reported, most with thymic abnormalities.1 MG-IM overlap has also been recognized as an immune-related adverse event from immune checkpoint inhibitor therapy.2

The Journal of Rheumatology
Johns Hopkins University (US), Shenandoah University (US), Johns Hopkins Medicine (US), National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
National Institutes of Health
Good health and well-being
Openalex Percentile: Top 14%
Myasthenia Gravis and Thymoma
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