A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion

In multiple sclerosis (MS), new or enlarging brain lesions often suggest disease activity, but infections or tumors may mimic relapse. We report a 35-year-old woman with MS whose enlarging thalamic lesion was ultimately diagnosed as diffuse midline glioma, underscoring the need for prompt evaluation of atypical MRI findings.

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Publication Details

Journal
Neurology Neuroimmunology & Neuroinflammation
Published
2026-10-15
DOI
https://doi.org/10.1212/nxi.0000000000200667
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion

Isabel Arrillaga‐Romany, Scott S. Zamvil, Eric C. Klawiter, Claire Riley et al.
Neurology Neuroimmunology & Neuroinflammation
Multiple Sclerosis Research Studies
article

A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion

Isabel Arrillaga‐Romany, Scott S. Zamvil, Eric C. Klawiter, Claire Riley, María Martínez-Lage, Justin T. Jordan, Myla D. Goldman, Nara Miriam Michaelson
article en

Abstract

In multiple sclerosis (MS), new or enlarging brain lesions often suggest disease activity, but infections or tumors may mimic relapse. We report a 35-year-old woman with MS whose enlarging thalamic lesion was ultimately diagnosed as diffuse midline glioma, underscoring the need for prompt evaluation of atypical MRI findings.

Neurology Neuroimmunology & NeuroinflammationVol. 13(6)
Beth Israel Deaconess Medical Center (US), Virginia Commonwealth University (US), Massachusetts General Hospital (US), Southwestern Medical Center (US), Center for Neuro-Oncology (US), Columbia University (US), The University of Texas Southwestern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 13%
Multiple Sclerosis Research Studies
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