Nontumor‐Specific mRNA Sensitization of Cold Tumors to Immune Checkpoint Blockade: Evidence, Bias, and Requirements for Translation

ABSTRACT Nontumor‐specific messenger RNA may sensitize cold tumors to checkpoint blockade, but survival estimates are heterogeneous, bias‐aligned analyses reveal no difference, and spreading is unproven.

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Publication Details

Journal
Advanced Oncology
Published
2026-10-15
DOI
https://doi.org/10.1002/adon.70007
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.00
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article

Nontumor‐Specific mRNA Sensitization of Cold Tumors to Immune Checkpoint Blockade: Evidence, Bias, and Requirements for Translation

Sarfaraz K. Niazi
Advanced Oncology
Cancer Immunotherapy and Biomarkers
article

Nontumor‐Specific mRNA Sensitization of Cold Tumors to Immune Checkpoint Blockade: Evidence, Bias, and Requirements for Translation

Sarfaraz K. Niazi
article en

Abstract

ABSTRACT Nontumor‐specific messenger RNA may sensitize cold tumors to checkpoint blockade, but survival estimates are heterogeneous, bias‐aligned analyses reveal no difference, and spreading is unproven.

Advanced OncologyVol. 1(1)
Washington State University Spokane (US)
Good health and well-being
Openalex Percentile: Top 17%
Cancer Immunotherapy and Biomarkers
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