Limited utility of consumer wearable APIs for predicting substance use and craving, despite model personalization
Abstract We explored the feasibility of predicting, using individually-tailored artificial intelligence (AI) models, substance use and craving from Fitbit data collected in free-living conditions. Most substances examined acutely raise heart rate, and craving is known to often involve autonomic arousal. Because heart rate responds to stress, exertion, and substance use differently between individuals, we sought to study in an exploratory experiment whether individualized artificial intelligence (AI) models could learn person-specific patterns that distinguish substance-related heart rate changes from other arousal when conditioned on current activity level. We also examined whether per-participant data coverage and participant adherence to the data collection protocol could explain gaps in performance. Sixteen participants contributed 47 participant–substance–task prediction scenarios (25 substance use, 22 craving) spanning six substances. For each scenario, we trained a model to predict ecological momentary assessment responses, comparing global supervised, global self-supervised, and personalized self-supervised modeling approaches. Discrimination was modest (mean AUROC 0.569–0.617) for all substances and for both craving and use prediction, and differences in data coverage and participant adherence did not explain performance gaps. These findings suggest that heart rate and step count from a consumer wristband carry limited substance-specific signal in isolation, and thus digital intervention research may gain more traction from targeting better-characterized antecedents such as stress than from predicting use or craving directly.
Authors
- Kristina T. Phillips (ORCID: https://orcid.org/0000-0001-7693-8845)
- Roberto Martín Benzo (ORCID: https://orcid.org/0000-0001-8634-6472)
- Christopher R. Slade (ORCID: https://orcid.org/0009-0002-5162-668X)
- Nhung Phuong Thi Nguyen (ORCID: https://orcid.org/0000-0002-8661-9597)
- Chanhyun Park (ORCID: https://orcid.org/0000-0002-1081-0950)
- Xuhai Xu (ORCID: https://orcid.org/0000-0001-5930-3899)
- Adrián Aguilera (ORCID: https://orcid.org/0000-0003-1773-8768)
- Agnik Banerjee (ORCID: https://orcid.org/0000-0001-6200-1947)
- Ali Kargarandehkordi (ORCID: https://orcid.org/0000-0002-2714-9476)
- Hiwot Belay Tadesse
- Peter Washington (ORCID: https://orcid.org/0000-0003-3276-4411)
- Finale Doshi-Velez
- Alexander Kostrinsky-Thomas
- Yinan Sun
- Haopeng Zhang
- Aditi Jaiswal
- Yang Qian
- Tanvir Islam
Institutions
- Brigham Young University (US)
- Brigham Young University–Hawaii (US)
- University of Hawaiʻi at Mānoa (US)
- Kaiser Permanente (US)
- Harvard University (US)
- George Mason University (US)
- University of California, San Francisco (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- The Ohio State University Wexner Medical Center (US)
- Kaiser Permanente Bernard J. Tyson School of Medicine (US)
- The Ohio State University (US)
- University of Maryland, College Park (US)
- Columbia University (US)
- The University of Texas at Austin (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- npj Biosensing
- Published
- 2026-10-14
- DOI
- https://doi.org/10.1038/s44328-026-00117-7
- Primary Topic
- Substance Abuse Treatment and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Institutes of Health
- National Institute of General Medical Sciences