Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes

Background: Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) remain the leading causes of exercise-related mortality in athletes. Research in recent years has produced substantial advances in the understanding of athlete-specific risk, the etiologic spectrum of SCA/SCD, and the tools available for screening and risk stratification. Methods: We performed a narrative review of the literature identified through PubMed/MEDLINE searches of related terms, supplemented by targeted searches and reference checking. Summary of the Review: In this narrative review, we synthesize updated evidence on the epidemiology, etiologies, screening, and emerging technologies relevant to SCA/SCD in athletes. Conclusions: Contemporary evaluation of SCA/SCD risk in athletes relies on multimodal, individualized assessment with longitudinal surveillance and shared decision-making. Emerging computational tools may further refine risk prediction, but current evidence remains limited.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-10-14
DOI
https://doi.org/10.3390/jcm15207920
Primary Topic
Cardiovascular Effects of Exercise
Type
article
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article

Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes

John Fritzlen, Jacob Cushing, Luke Hamar
Journal of Clinical Medicine
Cardiovascular Effects of Exercise
article

Frontiers in the Risk Stratification and Prevention of Sudden Cardiac Arrest and Death in Athletes

John Fritzlen, Jacob Cushing, Luke Hamar
article en

Abstract

Background: Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) remain the leading causes of exercise-related mortality in athletes. Research in recent years has produced substantial advances in the understanding of athlete-specific risk, the etiologic spectrum of SCA/SCD, and the tools available for screening and risk stratification. Methods: We performed a narrative review of the literature identified through PubMed/MEDLINE searches of related terms, supplemented by targeted searches and reference checking. Summary of the Review: In this narrative review, we synthesize updated evidence on the epidemiology, etiologies, screening, and emerging technologies relevant to SCA/SCD in athletes. Conclusions: Contemporary evaluation of SCA/SCD risk in athletes relies on multimodal, individualized assessment with longitudinal surveillance and shared decision-making. Emerging computational tools may further refine risk prediction, but current evidence remains limited.

Journal of Clinical MedicineVol. 15(20)
University of Kansas Medical Center (US)
Good health and well-being
Openalex Percentile: Top 12%
Cardiovascular Effects of Exercise
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