Stellate Ganglion Block for Treatment-Resistant Post-traumatic Stress Disorder: A Case Report

Post-traumatic stress disorder (PTSD) is a psychiatric condition that can develop following exposure to traumatic events and is characterized by intrusive memories, avoidance, negative changes in mood and cognition, and heightened arousal.A woman in her late 20s with bipolar I disorder, PTSD, and anorexia nervosa, binge-purge subtype, demonstrated minimal response to multiple medication trials targeting PTSD symptoms.Following administration of a stellate ganglion block (SGB), symptom scores decreased on the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Checklist for DSM-5 (PCL-5), although residual symptoms remained.This case highlights the potential role of SGB as an off-label therapeutic option for PTSD.

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Publication Details

Journal
Cureus
Published
2026-10-14
DOI
https://doi.org/10.7759/cureus.117912
Primary Topic
Posttraumatic Stress Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Stellate Ganglion Block for Treatment-Resistant Post-traumatic Stress Disorder: A Case Report

Elizabeth Francis
Cureus
Posttraumatic Stress Disorder Research
article

Stellate Ganglion Block for Treatment-Resistant Post-traumatic Stress Disorder: A Case Report

Elizabeth Francis
article en

Abstract

Post-traumatic stress disorder (PTSD) is a psychiatric condition that can develop following exposure to traumatic events and is characterized by intrusive memories, avoidance, negative changes in mood and cognition, and heightened arousal.A woman in her late 20s with bipolar I disorder, PTSD, and anorexia nervosa, binge-purge subtype, demonstrated minimal response to multiple medication trials targeting PTSD symptoms.Following administration of a stellate ganglion block (SGB), symptom scores decreased on the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Checklist for DSM-5 (PCL-5), although residual symptoms remained.This case highlights the potential role of SGB as an off-label therapeutic option for PTSD.

Cureus
Duke University (US)
Good health and well-being
Openalex Percentile: Top 9%
Posttraumatic Stress Disorder Research
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