Artificial intelligence in cardiovascular imaging and electrocardiography

Artificial intelligence (AI), particularly deep learning, is reshaping cardiovascular imaging and electrocardiography (ECG) by enabling automated acquisition support, quantification, disease detection, and risk prediction. Yet, high retrospective accuracy does not by itself establish transportability or clinical benefit. This narrative review first outlines the AI development lifecycle, with emphasis on data and label quality, architecture selection, patient-level data partitioning, calibration, external validation, and prospective evaluation. It then critically examines representative advances in ECG, echocardiography, cardiac magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear cardiology. Particular attention is given to three rapidly evolving areas: AI-enhanced ECG, video- and vision-language echocardiography, and volumetric CT and CMR analysis. We compare convolutional, transformer-based, hybrid, and generative approaches; summarize explainable-AI methods, including gradient-weighted class activation mapping (Grad-CAM), SHapley Additive exPlanations (SHAP), integrated gradients, and occlusion testing; and analyze failure modes arising from label, sampling, demographic, device, and temporal bias. Quantitative examples show that performance can deteriorate across institutions, demographic groups, and acquisition settings despite apparently strong internal validation. Future progress will depend on prospective workflow-based trials, multimodal foundation models with transparent benchmarks, lifecycle governance and regulation, and continuous post-deployment surveillance.

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Publication Details

Journal
Cardiology Plus
Published
2026-10-14
DOI
https://doi.org/10.1097/cp9.0000000000000174
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
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article

Artificial intelligence in cardiovascular imaging and electrocardiography

Yixiu Liang, Shuo Wang, Zilong Xiao
Cardiology Plus
Artificial Intelligence in Healthcare and Education
article

Artificial intelligence in cardiovascular imaging and electrocardiography

Yixiu Liang, Shuo Wang, Zilong Xiao
article en

Abstract

Artificial intelligence (AI), particularly deep learning, is reshaping cardiovascular imaging and electrocardiography (ECG) by enabling automated acquisition support, quantification, disease detection, and risk prediction. Yet, high retrospective accuracy does not by itself establish transportability or clinical benefit. This narrative review first outlines the AI development lifecycle, with emphasis on data and label quality, architecture selection, patient-level data partitioning, calibration, external validation, and prospective evaluation. It then critically examines representative advances in ECG, echocardiography, cardiac magnetic resonance (CMR), cardiac computed tomography (CT), and nuclear cardiology. Particular attention is given to three rapidly evolving areas: AI-enhanced ECG, video- and vision-language echocardiography, and volumetric CT and CMR analysis. We compare convolutional, transformer-based, hybrid, and generative approaches; summarize explainable-AI methods, including gradient-weighted class activation mapping (Grad-CAM), SHapley Additive exPlanations (SHAP), integrated gradients, and occlusion testing; and analyze failure modes arising from label, sampling, demographic, device, and temporal bias. Quantitative examples show that performance can deteriorate across institutions, demographic groups, and acquisition settings despite apparently strong internal validation. Future progress will depend on prospective workflow-based trials, multimodal foundation models with transparent benchmarks, lifecycle governance and regulation, and continuous post-deployment surveillance.

Cardiology Plus
Shanghai Medical College of Fudan University (CN), Fudan University (CN), Hammersmith Hospital (GB)
Good health and well-being
Openalex Percentile: Top 20%
Artificial Intelligence in Healthcare and Education
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