International Clinical Practice Guideline of Chinese Medicine: Functional Dyspepsia

ABSTRACT Background and Objective Functional dyspepsia (FD) is a disorder of gut–brain interaction characterized by recurrent upper gastrointestinal symptoms in the absence of identifiable organic disease. Traditional Chinese medicine (TCM) is increasingly used in its management. This guideline aims to provide standardized clinical recommendations for healthcare professionals managing adults with FD. Methods The guideline development group reviewed existing TCM guidelines and consensus statements, formulated key clinical questions, and systematically searched major Chinese and international databases. Evidence was assessed and graded using the TCM clinical evidence‐grading system. Recommendations were developed by integrating evidence synthesis with a structured consensus process, including Delphi surveys and expert panel meetings. Recommendation direction and strength were determined using a predefined grid‐based voting approach. Results The guideline provides recommendations on diagnostic principles, syndrome differentiation, herbal formulas, Chinese patent medicines, acupuncture and related external therapies, and lifestyle management. Recommendations incorporate available clinical evidence and expert consensus, with evidence levels and recommendation strength specified where applicable. Conclusions This guideline provides evidence‐informed and consensus‐based guidance on TCM management of adult FD. It aims to promote consistency in clinical practice and support appropriate, individualized treatment.

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Publication Details

Journal
Gut Medicine
Published
2026-10-14
DOI
https://doi.org/10.1002/gtm2.70019
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

International Clinical Practice Guideline of Chinese Medicine: Functional Dyspepsia

Liping Duan, Gengqing Song, Shengsheng Zhang, Han Jiang et al.
Gut Medicine
Gastrointestinal motility and disorders
article

International Clinical Practice Guideline of Chinese Medicine: Functional Dyspepsia

Liping Duan, Gengqing Song, Shengsheng Zhang, Han Jiang, Nicholas Joseph Talley, Xiaohua Hou, Peijing Rong, Jianping Liu, Wei Wei, Meiyun Ke, Fanya Yu, Liu Louis, Fengbin Liu, Wei Chen, Shiyi Zhang, Jiande D. Z. Chen
article en

Abstract

ABSTRACT Background and Objective Functional dyspepsia (FD) is a disorder of gut–brain interaction characterized by recurrent upper gastrointestinal symptoms in the absence of identifiable organic disease. Traditional Chinese medicine (TCM) is increasingly used in its management. This guideline aims to provide standardized clinical recommendations for healthcare professionals managing adults with FD. Methods The guideline development group reviewed existing TCM guidelines and consensus statements, formulated key clinical questions, and systematically searched major Chinese and international databases. Evidence was assessed and graded using the TCM clinical evidence‐grading system. Recommendations were developed by integrating evidence synthesis with a structured consensus process, including Delphi surveys and expert panel meetings. Recommendation direction and strength were determined using a predefined grid‐based voting approach. Results The guideline provides recommendations on diagnostic principles, syndrome differentiation, herbal formulas, Chinese patent medicines, acupuncture and related external therapies, and lifestyle management. Recommendations incorporate available clinical evidence and expert consensus, with evidence levels and recommendation strength specified where applicable. Conclusions This guideline provides evidence‐informed and consensus‐based guidance on TCM management of adult FD. It aims to promote consistency in clinical practice and support appropriate, individualized treatment.

Gut Medicine
Beijing University of Chinese Medicine (CN), Capital Medical University (CN), University of Toronto (CA), University of Michigan (US), Peking Union Medical College Hospital (CN), Hunter Medical Research Institute (AU), First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN), Michigan Medicine (US), Wangjing Hospital of China Academy of Chinese Medical Sciences (CN), Wuhan Union Hospital (CN), China Academy of Chinese Medical Sciences (CN), Peking University Third Hospital (CN), Beijing Hospital of Traditional Chinese Medicine (CN), Qilu Hospital of Shandong University (CN), National Health and Medical Research Council (AU), Huazhong University of Science and Technology (CN), Case Western Reserve University (US), University of Newcastle Australia (AU)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 10%
Gastrointestinal motility and disorders
DOIOpen Access PDFOpenAlex
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