Alveolar stem cells go beyond making gas-exchange cells to repair damaged airways

Alveolar type 2 (AT2) cells are the stem cells of the lung’s air sacs and are responsible for maintaining alveolar structure and gas exchange. A study that tracked AT2 cells shows that, after injury to the airway, they can also migrate between lung compartments and become bronchiolar cells to help repair damaged airways. Alveolar type 2 cells can migrate from the lung’s air sacs into the airways to repair damage there.

Publication Details

Journal
Nature
Published
2026-10-14
DOI
https://doi.org/10.1038/d41586-026-03085-0
Primary Topic
Neonatal Respiratory Health Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Alveolar stem cells go beyond making gas-exchange cells to repair damaged airways

Nature
Neonatal Respiratory Health Research
article

Alveolar stem cells go beyond making gas-exchange cells to repair damaged airways

article en

Abstract

Alveolar type 2 (AT2) cells are the stem cells of the lung’s air sacs and are responsible for maintaining alveolar structure and gas exchange. A study that tracked AT2 cells shows that, after injury to the airway, they can also migrate between lung compartments and become bronchiolar cells to help repair damaged airways. Alveolar type 2 cells can migrate from the lung’s air sacs into the airways to repair damage there.

Nature
Good health and well-being
Openalex Percentile: Top 13%
Neonatal Respiratory Health Research
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