Cellular diversity in neural organoids is critical for neurodegenerative disease modeling
Neuroinflammation and vascular dysfunction are hallmarks of most neurodegenerative diseases. For organoids intended to model neurodegeneration, immune, and vascular cells should therefore be considered fundamental components, rather than optional additions.
Authors
- Shi‐Yan Ng (ORCID: https://orcid.org/0000-0003-3418-2757)
- Shiying Liu
Institutions
- Agency for Science, Technology and Research (SG)
Publication Details
- Journal
- PLoS Biology
- Published
- 2026-10-14
- DOI
- https://doi.org/10.1371/journal.pbio.3004074
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation Singapore