Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management

Emphysematous pyelonephritis (EPN) is a rare, life-threatening necrotizing renal infection predominantly affecting diabetics. We report a 66-year-old female with uncontrolled type 2 diabetes who presented with right flank pain and fever. CT confirmed Class 2 EPN with gas confined to the renal parenchyma. Blood cultures grew Escherichia coli . She was successfully managed conservatively with imipenem-cilastatin, fluid resuscitation, and insulin therapy, avoiding surgery. This case highlights CT's role in early EPN diagnosis and demonstrates that tailored medical management can be a nephron-sparing alternative in selected patients.

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Publication Details

Journal
Radiology Case Reports
Published
2026-10-13
DOI
https://doi.org/10.1016/j.radcr.2026.09.055
Primary Topic
Urinary Tract Infections Management
Type
article
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article

Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management

JianKai Gao, Ya Gao
Radiology Case Reports
Urinary Tract Infections Management
article

Emphysematous pyelonephritis in a diabetic patient: A case report highlighting diagnostic challenges and successful conservative management

JianKai Gao, Ya Gao
article en

Abstract

Emphysematous pyelonephritis (EPN) is a rare, life-threatening necrotizing renal infection predominantly affecting diabetics. We report a 66-year-old female with uncontrolled type 2 diabetes who presented with right flank pain and fever. CT confirmed Class 2 EPN with gas confined to the renal parenchyma. Blood cultures grew Escherichia coli . She was successfully managed conservatively with imipenem-cilastatin, fluid resuscitation, and insulin therapy, avoiding surgery. This case highlights CT's role in early EPN diagnosis and demonstrates that tailored medical management can be a nephron-sparing alternative in selected patients.

Radiology Case ReportsVol. 21(12)
Fifth Affiliated Hospital of Zhengzhou University (CN)
Openalex Percentile: Top 12%
Urinary Tract Infections Management
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