Reassessing cardiometabolic health disparities among young adult sexual minority women: Evidence from a population-based cohort
PURPOSE: We compared objective measures of cardiometabolic health (CMH) between women who identify as lesbian/gay or bisexual (LGB) and women who identify as heterosexual. In addition, we aimed to test whether group differences in stress reactivity partially explained disparities in CMH health. METHODS: Participants from a longitudinal study were identified for enrollment in 2017. The LGB group self-identified as LGB in 2017 (n = 239), and the heterosexual group identified as straight or heterosexual in each year that sexual identity was asked (study years 2010-2017) (n = 160). CMH was assessed via measurements and biomarkers, and stress reactivity via heart rate variability and cortisol levels during a social stress test. Participants also provided self-reports of stress and health. We tested group differences using sexual identity at Study Year 17, at the time of the visit, and as a proportion of years identifying as LGB. RESULTS: Group differences were tested using t-tests for continuous measures, logistic regression for dichotomous measures, and repeated-measures ANOVA for change over time. There were no significant differences in measures of CMH or stress reactivity by sexual identity group. LGB participants had worse self-reported health and higher levels of stress compared to heterosexual participants. CONCLUSION: We discuss several frameworks for interpreting the present results of no differences in objective markers of health in the context of the existing literature, including developmental, socio-political, and methodological frameworks, and suggest directions for research to link the previous research with the results of the current study.
Authors
- Alicia K. Matthews (ORCID: https://orcid.org/0000-0002-0074-681X)
- Kate E. Keenan (ORCID: https://orcid.org/0000-0002-1775-8171)
- Stephanie D. Stepp (ORCID: https://orcid.org/0000-0002-2664-8206)
- KRISTEN WROBLEWSKI
- Alida Bouris
Institutions
- University of Pittsburgh (US)
- University of Chicago (US)
- Rush University (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-10-13
- DOI
- https://doi.org/10.1371/journal.pone.0358185
- Primary Topic
- LGBTQ Health, Identity, and Policy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute