Vascular Patterning in Morphea Mimicking a Capillary Malformation: Case Report and Review of the Literature

Early, inflammatory morphea can rarely mimic an acquired capillary malformation (CM), and emerging evidence suggests that endothelial injury may precede fibrosis in morphea, with vascular abnormalities driving immune recruitment and fibroblast activation. We present a pediatric case of inflammatory linear morphea initially misdiagnosed as an acquired CM. Dynamic optical coherence tomography (OCT) demonstrated a dense, superficial vascular network, resembling that seen in genetically confirmed capillary malformations. This case highlights the key clinical and morphologic features of morphea, with clinical pearls to differentiate from acquired CMs. Early recognition of this clinical mimic is critical to prevent irreversible atrophy and fibrosis.

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Publication Details

Journal
Pediatric Dermatology
Published
2026-10-13
DOI
https://doi.org/10.1111/pde.70366
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Vascular Patterning in Morphea Mimicking a Capillary Malformation: Case Report and Review of the Literature

Yvonne E. Chiu, D Zhang, Ashley Ng, Daniel D Bennett et al.
Pediatric Dermatology
Systemic Sclerosis and Related Diseases
article

Vascular Patterning in Morphea Mimicking a Capillary Malformation: Case Report and Review of the Literature

Yvonne E. Chiu, D Zhang, Ashley Ng, Daniel D Bennett, Kristen Marie Kathryn Kelly, Beth A. Drolet, Lisa M. Arkin, Hannah J. Kolarik
article en

Abstract

Early, inflammatory morphea can rarely mimic an acquired capillary malformation (CM), and emerging evidence suggests that endothelial injury may precede fibrosis in morphea, with vascular abnormalities driving immune recruitment and fibroblast activation. We present a pediatric case of inflammatory linear morphea initially misdiagnosed as an acquired CM. Dynamic optical coherence tomography (OCT) demonstrated a dense, superficial vascular network, resembling that seen in genetically confirmed capillary malformations. This case highlights the key clinical and morphologic features of morphea, with clinical pearls to differentiate from acquired CMs. Early recognition of this clinical mimic is critical to prevent irreversible atrophy and fibrosis.

Pediatric Dermatology
University of Wisconsin–Madison (US), University of California, Irvine (US), Medical College of Wisconsin (US)
Openalex Percentile: Top 13%
Systemic Sclerosis and Related Diseases
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