Does Time Truly Heal All? A Prospective Cohort Study of 6- To 12-Month Recovery Transitions After Traumatic Injury

BACKGROUND: Recovery after traumatic injury may extend beyond conventional follow-up, but longer-term changes in function, quality of life (QoL), and return to work (RTW) remain incompletely characterized. STUDY DESIGN: English- or Spanish-speaking patients with Injury Severity Score ≥9 from three US Level I trauma centers completed telephone surveys 6 and 12 months after injury. Recovery was characterized as improved, stable, or declined between timepoints. Function was assessed across six Trauma Quality of Life domains; QoL and RTW by self-report; and mental health using GAD-7, PHQ-8, and Breslau PTSD scales. Multivariable logistic regression evaluated predictors of QoL decline. Sensitivity analyses examined traumatic brain injury (TBI), isolated long bone fracture, and general trauma. RESULTS: Among 1,894 patients, 49% of those impaired at 6 months improved, 41% were unchanged, and 11% worsened by 12 months. Patients ≥65 more often improved (20% vs. 16%) and declined (16% vs. 9%) than those <65; surgical patients more often improved (20% vs. 16%). QoL improved in 22%, remained stable in 56%, and declined in 22%. TBI patients had the greatest functional improvement (55%), whereas long bone fracture patients had the greatest QoL improvement (26%). Weak social support (aOR 3.68) and mental health symptoms were associated with QoL decline. RTW reached 61% by 6 months; 74% of non-returners remained so at 12 months. CONCLUSIONS: Recovery remains dynamic beyond 6 months after trauma, supporting extended follow-up and individualized rehabilitation. Associations of mental health symptoms and weak social support with QoL decline support incorporating their assessment into post-injury care.

Authors

Institutions

Publication Details

Journal
Journal of the American College of Surgeons
Published
2026-10-13
DOI
https://doi.org/10.1097/xcs.0000000000002257
Primary Topic
Trauma and Emergency Care Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Does Time Truly Heal All? A Prospective Cohort Study of 6- To 12-Month Recovery Transitions After Traumatic Injury

Juan P. Herrera‐Escobar, Alexander J. Ordoobadi, Manuel Castillo Angeles, Avery A. Thompson et al.
Journal of the American College of Surgeons
Trauma and Emergency Care Studies
article

Does Time Truly Heal All? A Prospective Cohort Study of 6- To 12-Month Recovery Transitions After Traumatic Injury

Juan P. Herrera‐Escobar, Alexander J. Ordoobadi, Manuel Castillo Angeles, Avery A. Thompson, Sabrina Elena Sanchez, Saba Ilkhani, Geoffrey A. Anderson, John T Figi, Ali Salim, Haytham Kaafarani
article en

Abstract

BACKGROUND: Recovery after traumatic injury may extend beyond conventional follow-up, but longer-term changes in function, quality of life (QoL), and return to work (RTW) remain incompletely characterized. STUDY DESIGN: English- or Spanish-speaking patients with Injury Severity Score ≥9 from three US Level I trauma centers completed telephone surveys 6 and 12 months after injury. Recovery was characterized as improved, stable, or declined between timepoints. Function was assessed across six Trauma Quality of Life domains; QoL and RTW by self-report; and mental health using GAD-7, PHQ-8, and Breslau PTSD scales. Multivariable logistic regression evaluated predictors of QoL decline. Sensitivity analyses examined traumatic brain injury (TBI), isolated long bone fracture, and general trauma. RESULTS: Among 1,894 patients, 49% of those impaired at 6 months improved, 41% were unchanged, and 11% worsened by 12 months. Patients ≥65 more often improved (20% vs. 16%) and declined (16% vs. 9%) than those <65; surgical patients more often improved (20% vs. 16%). QoL improved in 22%, remained stable in 56%, and declined in 22%. TBI patients had the greatest functional improvement (55%), whereas long bone fracture patients had the greatest QoL improvement (26%). Weak social support (aOR 3.68) and mental health symptoms were associated with QoL decline. RTW reached 61% by 6 months; 74% of non-returners remained so at 12 months. CONCLUSIONS: Recovery remains dynamic beyond 6 months after trauma, supporting extended follow-up and individualized rehabilitation. Associations of mental health symptoms and weak social support with QoL decline support incorporating their assessment into post-injury care.

Journal of the American College of Surgeons
Boston University (US), University of Southern California (US), Brigham and Women's Hospital (US), Boston Medical Center (US), Massachusetts General Hospital (US), Center for Systems Biology (US)
Openalex Percentile: Top 10%
Trauma and Emergency Care Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.