Does Time Truly Heal All? A Prospective Cohort Study of 6- To 12-Month Recovery Transitions After Traumatic Injury
BACKGROUND: Recovery after traumatic injury may extend beyond conventional follow-up, but longer-term changes in function, quality of life (QoL), and return to work (RTW) remain incompletely characterized. STUDY DESIGN: English- or Spanish-speaking patients with Injury Severity Score ≥9 from three US Level I trauma centers completed telephone surveys 6 and 12 months after injury. Recovery was characterized as improved, stable, or declined between timepoints. Function was assessed across six Trauma Quality of Life domains; QoL and RTW by self-report; and mental health using GAD-7, PHQ-8, and Breslau PTSD scales. Multivariable logistic regression evaluated predictors of QoL decline. Sensitivity analyses examined traumatic brain injury (TBI), isolated long bone fracture, and general trauma. RESULTS: Among 1,894 patients, 49% of those impaired at 6 months improved, 41% were unchanged, and 11% worsened by 12 months. Patients ≥65 more often improved (20% vs. 16%) and declined (16% vs. 9%) than those <65; surgical patients more often improved (20% vs. 16%). QoL improved in 22%, remained stable in 56%, and declined in 22%. TBI patients had the greatest functional improvement (55%), whereas long bone fracture patients had the greatest QoL improvement (26%). Weak social support (aOR 3.68) and mental health symptoms were associated with QoL decline. RTW reached 61% by 6 months; 74% of non-returners remained so at 12 months. CONCLUSIONS: Recovery remains dynamic beyond 6 months after trauma, supporting extended follow-up and individualized rehabilitation. Associations of mental health symptoms and weak social support with QoL decline support incorporating their assessment into post-injury care.
Authors
- Juan P. Herrera‐Escobar (ORCID: https://orcid.org/0000-0002-3496-1470)
- Alexander J. Ordoobadi (ORCID: https://orcid.org/0000-0002-2507-6373)
- Manuel Castillo Angeles
- Avery A. Thompson (ORCID: https://orcid.org/0000-0003-1330-0611)
- Sabrina Elena Sanchez (ORCID: https://orcid.org/0000-0003-2437-9505)
- Saba Ilkhani (ORCID: https://orcid.org/0000-0003-1233-1141)
- Geoffrey A. Anderson (ORCID: https://orcid.org/0000-0001-5756-995X)
- John T Figi (ORCID: https://orcid.org/0000-0002-7412-0246)
- Ali Salim
- Haytham Kaafarani
Institutions
- Boston University (US)
- University of Southern California (US)
- Brigham and Women's Hospital (US)
- Boston Medical Center (US)
- Massachusetts General Hospital (US)
- Center for Systems Biology (US)
Publication Details
- Journal
- Journal of the American College of Surgeons
- Published
- 2026-10-13
- DOI
- https://doi.org/10.1097/xcs.0000000000002257
- Primary Topic
- Trauma and Emergency Care Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00