A CLASSICAL DRUG REVIEW ON NISHA AMALAKI CHURNA W.S.R. TO PRAMEHA (DIABETES MELLITUS TYPE - 2)

Background: Prameha (Diabetes mellitus Type - 2) is Santarpanajanya Vyadhi. About 90% of the estimated 387 million cases of diabetes globally as of 2014 were type-2. According to WHO predictions, emerging nations will bear a significant portion of the burden. Nisha Amalaki Churna is a formulation consists of herbal drugs as mentioned in Ashtanga Hridayam. Material and Methods: Ayurvedic texts, as well as the data bases Google scholar, PubMed, Medline, AYUSH Research Portal, and Digital Helpline for Ayurveda Research Articles (DHARA), Research Gate web-based search engines, journal, were used to search for relevant literature and information. Result: Prameha (Diabetes mellitus Type - 2) is Tridoshaja Vyadhi, Acharyas have mainly emphasized on vitiation of Kapha Dosha and also emphasized on Medovriddhi and Medodhatwagnimandhya. Nisha Amalaki Churna referred in Ashtanga Hridayam was reviewed, analysed in detail. Drugs are having Pramehara property directly acting on etiopathogenesis of Madhumeha. Tikta, Katu, Kashaya Rasa, Laghu, Ruksha Guna, Ushna Virya and Katu Vipaka may correct Kapha Dushti and Medo Dhatu Dushti. Laghu, Ruksha Guna by their Deepana Pachana property may remove Medodhatwagnimandya there by correcting the Medo Dhatu Dushti. Pharmacological activity like anti-diabetic, anti-hyperlipidemic, antiobesity, etc effect were also reported. Conclusion: The classical formulation Nisha Amalaki Churna is a very unique and finds its great utility in management of Prameha (Diabetes mellitus Type-2).