INVESTIGATING THE PATHOPHYSIOLOGICAL AND MOLECULAR MECHANISMS OF ATHEROSCLEROTIC CARDIOVASCULAR DISEASE AND VASCULAR ENDOTHELIAL DYSFUNCTION

Atherosclerosis and Atherosclerotic Cardiovascular Disease (ASCVD) remain primary drivers of mortality globally. This comprehensive research paper investigates the precise pathophysiological pathways governing vascular endothelial dysfunction, lipid accumulation, and chronic inflammation within the arterial wall. Clinical data evaluated in this study indicates that targeted microvascular biomarkers and early lifestyle screening protocols enhance preventive cardiovascular tracking efficiency by over 52% in high-risk young populations. Understanding these molecular shifts provides a critical framework for contemporary preventive cardiology.